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Method for measuring DNA molecular mass according to resonance principle

A DNA molecule and quality technology, applied in measuring devices, weighing equipment using elastically deformable parts, weighing, etc., can solve the problems of small DNA molecular weight and inability to measure, and achieve the effect of simple measurement and simple principle

Inactive Publication Date: 2016-08-24
CHANGZHOU UNIV
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Problems solved by technology

However, because the molecular mass of DNA is too small, the existing static mass measurement equipment cannot accurately measure it

Method used

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  • Method for measuring DNA molecular mass according to resonance principle
  • Method for measuring DNA molecular mass according to resonance principle

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Embodiment Construction

[0015] The present invention will be further described in detail below in conjunction with the accompanying drawings and specific embodiments.

[0016] see figure 1 As shown, a method for measuring DNA molecular mass using the resonance principle of the present invention includes an exciter 4, a hinge support A21, a hinge support B22, and two ends are respectively installed on the hinge support A21 and the hinge support B22 The micro-Charpy 32, the DNA molecular adsorption layer 31 installed on the micro-Charpy 32, the DNA molecule 1 to be measured, and the amplitude receiver 5 installed on the micro-Charpy 32.

[0017] see figure 1 and figure 2 As shown, the method for measuring the molecular mass of DNA using the resonance principle, the specific steps are as follows:

[0018] see figure 1 and figure 2 As shown, the exciter 4 is used to act on the micro-simply-supported beam 32 to make it vibrate freely; the amplitude receiver 5 is used to receive the amplitude of the...

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Abstract

The invention discloses a method for measuring DNA molecular mass by according to a resonance principle, and belongs to the field of detection and weighing of organic macromolecular mass. The system comprises a vibration exciter, a hinged support A, a hinged support B, a micro simply supported beam of which two ends are respectively assembled on the hinged support A and the hinged support B, a DNA molecular adsorption layer assembled on the micro simply supported beam, a DNA molecule to-be-measured, and an amplitude receiver assembled on the micro simply supported beam. The micro simply supported beam is subjected to vibration excitation so as to freely vibrate by the vibration exciter, and the amplitude receiver receives the corresponding amplitude and vibration frequency, so that the DNA molecular mass can be calculated. The method for measuring DNA molecular mass through the resonance principle disclosed by the invention is simple in principle and high in measurement accuracy.

Description

technical field [0001] The invention mainly relates to the field of detection and weighing of organic macromolecular mass, in particular to a method for measuring DNA molecular mass by using the resonance principle. Background technique [0002] DNA molecules are the main genetic material. Most of the infections of various human diseases can be reflected in the corresponding DNA molecular structure and quality changes. Therefore, it is of great significance to quickly and effectively weigh or detect the molecular quality of DNA. However, due to the small molecular mass of DNA, existing static mass measurement equipment cannot accurately measure it. Therefore, it is of great significance to design a device for dynamically measuring DNA molecules. Contents of the invention [0003] The technical problem to be solved by the present invention is: aiming at the technical problems existing in the prior art, the present invention provides a method for measuring DNA molecular mas...

Claims

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Application Information

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IPC IPC(8): G01G3/16
CPCG01G3/165
Inventor 班书昊李晓艳蒋学东何云松席仁强徐然谭邹卿
Owner CHANGZHOU UNIV
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