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A system and a corresponding method for estimating respiratory drive of mechanically ventilated patients

A mechanical ventilation, breathing-driven technology, used in respirator, drug devices, other medical devices, etc.

Active Publication Date: 2016-06-22
COVIDIEN LP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

An inherent disadvantage of this approach is the need to measure nerve drive through electrodes that are typically inserted into the septum in the esophagus

Method used

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  • A system and a corresponding method for estimating respiratory drive of mechanically ventilated patients
  • A system and a corresponding method for estimating respiratory drive of mechanically ventilated patients
  • A system and a corresponding method for estimating respiratory drive of mechanically ventilated patients

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0088] Figure 4 and 5 Illustrates the use of samples from two patients (each Figure 1 name) technology of the data collected. exist Figure 4 , showing the change in tidal volume (Vt) versus A) respiratory rate, B) end-tidal CO 2 and C) Plotting of arterial pH. Figure 4 Dashed curves in A represent the responses of these variables from model simulations assuming normal muscle and chemical responses, normal values ​​for metabolism such as tissue CO2 production rates, and normal values ​​for the acid-base status of blood and CSF. painted Figure 4 Stars, solid circles, crosses, oblique crosses, open circles, and triangles on A-C indicate data collected at different values ​​of Vt, each symbol representing a different value of the ventilator setting on the ventilator, Vt_SET. It should be noted that this data has been collected and plotted with volume as a variable, but pressure is instead applied as a variable in clinical practice. However, this is equivalent to what a...

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PUM

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Abstract

The present invention relates to a system (10) and a corresponding method for estimating the respiratory drive (R_DRIVE) of mechanically ventilated patients, and for preferably apportioning this respiratory drive into one, or more, components related to the chemical drive - i.e. the drive due to the chemoreceptor response- and / or the muscular drive - i.e. the contraction of respiratory muscles, for example the diaphragm. The principle of the invention is that respiratory drive can be obtained from measuring the patient's response to small changes in mechanical ventilation settings (Vt_SET), and that this can be apportioned into chemical and / or muscular effects depending upon the changes in respiratory frequency, and / or arterial or end tidal CO2 levels, and / or arterial blood p H.

Description

technical field [0001] The present invention relates to a system and corresponding method for estimating respiratory drive of a mechanically ventilated patient. More specifically, in order to assign this respiratory drive into one or more components related to the chemical drive, i.e., the drive due to chemoreceptor responses, and / or the muscular drive, i.e., the activation of the respiratory muscles such as the diaphragm shrink. Background technique [0002] Patients in intensive care units often receive mechanical support for their ventilation. Selection of the appropriate level of mechanical ventilation is important and has been shown to reduce mortality [1]. [0003] It should be noted that a device or system capable of administering mechanical ventilation is sometimes referred to as an artificial ventilator, life support device, or more generally, a ventilator. [0004] Typically, patients are ventilated in "support" mode. In these modes, the patient has some respir...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M16/00A61M16/12
CPCA61M16/12A61M2016/0027A61M2016/0039A61M2016/0042A61M2202/0464A61M2230/202A61M2230/205A61M2230/208A61M2230/42A61M2230/432A61M2230/435A61M16/026A61M16/0003A61M16/0069A61M2205/3334
Inventor 斯蒂芬·爱德华·雷斯达恩·斯蒂佩尔·卡尔宾塞巴斯蒂安·拉腊扎·里科
Owner COVIDIEN LP
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