Full-ingredient Chinese herbal medicine rhizoma typhonii granule detection method based on terahertz spectroscopy technology

A spectral technology and spectral detection technology, which is applied in the detection field of the Chinese herbal medicine Bai Fuzi in full-component granules, can solve the problems of low measurement repeatability and correlation, difficulty in obtaining fingerprint peaks of Chinese herbal medicines, and large interference factors. The detection speed is fast, the cost is low, and the effect of avoiding pollution

Inactive Publication Date: 2015-12-02
DAHENG NEW EPOCH TECH
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Problems solved by technology

However, the research objects of these terahertz tests are still limited to the original unprocessed Chinese medicinal materials or herbal medicinal materials. This form of medicinal materials has not been purified, so impurity molecules and other interference factors to the spectrum are very large, and the measurement repetition The correlation and correlation are not high, and in the limited range of 2.6THz, it is difficult to obtain the obvious characteristic fingerprint peaks of Chinese herbal medicines experimentally.

Method used

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  • Full-ingredient Chinese herbal medicine rhizoma typhonii granule detection method based on terahertz spectroscopy technology
  • Full-ingredient Chinese herbal medicine rhizoma typhonii granule detection method based on terahertz spectroscopy technology

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Embodiment 1

[0030] The present embodiment provides a method for detecting Aconite Radix using terahertz time-domain spectroscopy, which includes the following steps:

[0031] 1), sample preparation: the sample used is the full-component traditional Chinese medicine Radix Aconiti granules produced by Beijing Kangrentang Pharmaceutical Co., Ltd., weigh about 60 mg of Rhizoma Radix with an electronic balance, and then grind it into a fine powder in a mortar. Next, set the shape in the tablet press, increase the pressure to 5 tons, and take 8 minutes to obtain a disc with a diameter of 13 mm, smooth on both sides, and a thickness of less than 0.4 mm.

[0032] 2), sample test: turn on the laser until the output power is stable, calibrate the light collimation in the optical path; turn on the laptop, set the measurement parameters on the program panel of the terahertz spectroscopy system software, and measure after the laser warms up for one hour; Put the prepared empty sample rack into the sam...

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Abstract

The invention relates to the field of Chinese herbal medicine detection, in particular to a full-ingredient Chinese herbal medicine rhizoma typhonii granule detection method based on the terahertz spectroscopy technology. According to the detection method, full-ingredient Chinese herbal medicine granules are represented through the wide-frequency-band terahertz spectrum technology, fingerprint peaks within the wide frequency spectrum band are obtained, and full-ingredient Chinese herbal medicine granules in different categories are distinguished through the characteristics of the terahertz fingerprint peaks within the wide frequency band. The method solves the problems about measurement of spectrum representation of the full-ingredient Chinese herbal medicine granules and category distinguishing; assistance of chemical reagents is reduced, and the detection method is a pure physical detection method; the method is easy to operate, high in data processing speed and accurate in result.

Description

technical field [0001] The invention relates to the field of detection of traditional Chinese medicinal materials, in particular to a detection method of the Chinese herbal medicine Aconite Radix in full-component granules based on terahertz spectroscopy. Background technique [0002] Chinese medicine extract is a new product of traditional Chinese herbal medicine combined with modern pharmaceutical technology. Establishing effective analysis, identification and identification methods will help Chinese medicine extract to promote the international market of Chinese herbal medicine. At present, traditional Chinese medicine extracts are usually a single compound or a complex mixture system such as full-ingredient extract granules. Traditional Chinese medicine is a complex mixture system. The advantage of traditional Chinese medicine lies in "multi-armed joint operations", that is, compound prescriptions to treat diseases. The theory of yin and yang and five elements is often u...

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Application Information

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IPC IPC(8): G01N21/3586G01N21/3563
Inventor 于志宇吕丽丽刘尚建张存林
Owner DAHENG NEW EPOCH TECH
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