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Extraction method and application of plant composition containing serenoa repens

An extraction method and composition technology, which are applied in the field of extraction of plant compositions containing saw palmetto, can solve the problems of large dosage, backwardness, and many impurities in patients, and achieve the effect of reducing the dosage

Inactive Publication Date: 2015-12-02
NANJING ZHENGLIANG MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the prior art, there is no report on the use of microwave technology in the extraction and preparation of plant compositions containing saw palmetto. However, the method of decocting in water is rough, backward, and has many impurities, which leads to excessive dosage for patients and is inconvenient to take. , seriously affecting the clinical application of this product

Method used

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  • Extraction method and application of plant composition containing serenoa repens

Examples

Experimental program
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Effect test

Embodiment 1

[0014] Take 100 parts of saw palmetto, 50 parts of horned ginseng, 40 parts of mynah tongue, and 70 parts of white-backed leaves, crush them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W. 2 times, 4-8 minutes each time, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, concentrate and dry , to obtain the microwave extract, and add conventional excipients to prepare tablets, each tablet 0.4g.

Embodiment 2

[0016] Take 100 parts of saw palmetto, 50 parts of horned ginseng, 40 parts of mynah tongue, and 70 parts of white-backed leaves, crush them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W. 2 times, 4-8 minutes each time, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, concentrate and dry , to obtain a microwave extract, which is prepared into capsules by adding conventional auxiliary materials.

Embodiment 3

[0018] Take 100 parts of saw palmetto, 50 parts of horned ginseng, 40 parts of mynah tongue, and 70 parts of white-backed leaves, crush them, add 2L of 70% ethanol, and put them into a microwave extraction device for microwave extraction. The extraction power is 400-600W. 2 times, 4-8 minutes each time, combine the extracts, concentrate, add to D101 macroporous adsorption resin column, elute with 50% ethanol, collect 5 times the column volume eluate, recover ethanol under reduced pressure, concentrate and dry , to obtain a microwave extract, which is prepared into granules by adding conventional auxiliary materials.

[0019] Saw palmetto, also known as saw palmetto leaves or saw palmetto, scientifically named "Sabah palm", belongs to the palm family shrubs, usually grows in hot climate areas in North and South America, and its saw palmetto Serenoarepens (bartram) small ripe dry fruit Available for medicinal purposes.

[0020] Radix Ginseng is Polygonatum kansuense Maxim., a p...

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Abstract

The invention provides an extraction method of a plant composition containing serenoa repens. The plant composition is prepared from 100 parts of serenoa repens, 50 parts of whorledleaf solomonseal rhizome, 40 parts of pineleaf hedyotis herbs and 70 parts of mallotus apelta by adopting the microwave extraction method, therefore, the content is greatly increased, and the using amount is decreased. The invention further provides an application of the plant composition containing the serenoa repens in preparation of medicine for inhibiting proliferation of xenopus laevis nephrocyte ACTK1.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to an extraction method and application of a plant composition containing saw palmetto. Background technique [0002] The plant composition containing saw palmetto is made of 100 parts of saw palmetto, 50 parts of horned ginseng, 40 parts of mynah tongue, and 70 parts of white back leaf as raw materials. The current extraction method is to add water and decoct twice, each time After 2-3 hours, combine the decoction, filter, concentrate into a thick paste, granulate, dry, and coat with sugar. [0003] In the prior art, there is no report on the use of microwave technology in the extraction and preparation of plant compositions containing saw palmetto. However, the method of decocting in water is rough, backward, and has many impurities, which leads to excessive dosage for patients and is inconvenient to take. , Seriously affecting the clinical appli...

Claims

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Application Information

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IPC IPC(8): A61K36/8969
Inventor 赵明亮
Owner NANJING ZHENGLIANG MEDICAL TECH
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