Medicine composition for treating macular oedema

A technology of macular edema and composition, which is applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of retinal thickness increase, macular edema, affecting vision recovery, etc., and achieve the effect of delaying and preventing the formation and significant curative effect

Inactive Publication Date: 2015-11-11
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The inflammatory reaction increases the permeability of capillaries in the macular area, resulting in the accumulation of extracellular fluid,

Method used

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  • Medicine composition for treating macular oedema
  • Medicine composition for treating macular oedema
  • Medicine composition for treating macular oedema

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Embodiment 1: The pharmaceutical composition and preparation method thereof for the treatment of macular edema

[0034] The composition and parts by weight of the crude drug of the pharmaceutical composition for the treatment of macular edema are:

[0035] 95 parts by weight of anarch root, 75 parts by weight, 75 parts by weight, 75 parts by weight, 55 parts by weight, of rosette thistle, 35 parts by weight, 4.5 parts by weight, 4.5 parts by weight, of alisatiol B;

[0036] Preparation:

[0037] (1) According to the ratio of the raw materials, take the glycosides, styloides, anarchigen, and rosettes, mix them evenly, use ethanol with a concentration of 50% by weight as a solvent, and extract them by warm soaking at 60°C, and the number of extractions is 5 times , each extraction time is 1 hour, each time the amount of solvent is 15 times of the total weight of the above-mentioned medicinal materials, filtered, the extract is recovered from ethanol, concentrated to a re...

Embodiment 2

[0039] Embodiment 2: the pharmaceutical composition for the treatment of macular edema and its preparation method

[0040] The composition and parts by weight of the crude drug of the pharmaceutical composition for the treatment of macular edema are:

[0041] 90 parts by weight of anarch root, 80 parts by weight of glycopyrrolate, 50 parts by weight of rosette flower 50 parts by weight, 40 parts by weight of podocarpus resinol, 3 parts by weight of alisatiol B2;

[0042] Preparation:

[0043] (1) According to the ratio of the raw materials, take the glycosides, styloides, anarchigen, and rosettes, mix them evenly, use ethanol with a concentration of 50% by weight as a solvent, and extract them by warm soaking at 60°C, and the number of extractions is 5 times , each extraction time is 1 hour, each time the amount of solvent is 15 times of the total weight of the above-mentioned medicinal materials, filtered, the extract is recovered from ethanol, concentrated to a relative den...

Embodiment 3

[0045] Embodiment 3: the pharmaceutical composition and preparation method thereof for the treatment of macular edema

[0046] The composition and parts by weight of the crude drug of the pharmaceutical composition for the treatment of macular edema are:

[0047] 100 parts by weight of anarch root, 70 parts by weight of glycopyrrolate, 60 parts by weight of rosette flower, 30 parts by weight of podocarpus resinol, 6 parts by weight of alisatiol B1 by weight;

[0048] Preparation:

[0049] (1) According to the ratio of the raw materials, take the glycosides, styloides, anarchigen, and rosettes, mix them evenly, use ethanol with a concentration of 50% by weight as a solvent, and extract them by warm soaking at 60°C, and the number of extractions is 5 times , each extraction time is 1 hour, each time the amount of solvent is 15 times of the total weight of the above-mentioned medicinal materials, filtered, the extract is recovered from ethanol, concentrated to a relative density...

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PUM

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Abstract

The invention discloses a medicine composition for treating macular oedema. The medicine composition uses pyrethrum cinerariifolium roots, allyl amyl glycolate, lomatogonium carinthiacum, a rosette thistle herb, matairesinol and orientalol B as raw material medicines, is prepared according to proportions, can be prepared into various preparations by adopting a conventional preparation technology and is remarkable in effect of treating the macular oedema.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a pharmaceutical composition for treating macular edema. Background technique [0002] Macular edema is a common complication after phacoemulsification (referred to as phacoemulsification), with an incidence rate of 20% to 30%, and the peak period is 6 to 10 weeks after surgery. Patients with diabetes mellitus (DM) have a higher incidence of macular edema after phacoemulsification. Although surgical techniques are becoming more mature, the damage to the blood-aqueous humor barrier during the operation is slight and short-lived, but the damage to the blood-retinal barrier is still inevitable, which can easily lead to leakage of capillaries around the fovea of ​​the macula, resulting in the accumulation of fluid between the retinal layers. Edema occurs. Foreign studies have found that postoperative vision recovery in DM patients is worse than in simple catar...

Claims

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Application Information

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IPC IPC(8): A61K36/51A61P7/10A61P27/12A61K31/575A61K31/58
Inventor 张秀华
Owner JINAN XINGYI MEDICAL TECH
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