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Eye drops for alleviating dry eye syndrome and preparation method thereof

A technology for eye drops and dry eye syndrome, which is applied in the field of eye drops and its preparation, and achieves the effects of simple preparation method, small side effects and good effect

Active Publication Date: 2018-06-19
杭州瑟尔弗生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] So far, there are no eye drops prepared with vitamin A, vitamin E, hydroxypropyl methylcellulose, dandelion and / or dandelion extract, witch hazel, plum kernels, and alpine meadowsweet as main raw materials. related technology

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] In terms of mass percentage, it will account for the total amount of 0.4% vitamin A, 0.4% vitamin E, 0.3% hydroxypropyl methylcellulose, 0.3% dandelion, 0.2% witch hazel, 0.2% plum kernel, 0.2% alpine floss A total of 7 raw materials of chrysanthemum are broken into powder and mixed evenly. Because vitamins A and E are not resistant to high temperature, they are sterilized by radiation; after sterilizing the sealable stainless steel container at high temperature, add water for injection accounting for 98% of the total. Keep at room temperature, then add sterilized 0.4% vitamin A, 0.4% vitamin E, 0.3% hydroxypropyl methylcellulose, 0.3% dandelion, 0.2% witch hazel, 0.2% plum kernel, 0.2% alpine spirea , a mixture of 98% water for injection, ultrasonic stirring and soaking for 48 hours, stirring once every 8 hours during the soaking process; filtering out insoluble impurities, completing sterilization in a packaging machine, subpackaging, and sealing to obtain the finished...

Embodiment 2

[0049] In terms of mass percentage, it will account for the total amount of 0.6% vitamin A, 0.6% vitamin E, 0.6% hydroxypropyl methylcellulose, 0.6% dandelion, 0.6% witch hazel, 0.6% plum kernel, 0.6% alpine floss A total of 7 raw materials of chrysanthemum are broken into powder and mixed evenly. Because vitamin A and E are not resistant to high temperature, they are sterilized by radiation; after sterilizing the sealable stainless steel container at high temperature, add water for injection accounting for 95.8% of the total. Keep at room temperature, then add sterilized 0.6% vitamin A, 0.6% vitamin E, 0.6% hydroxypropyl methylcellulose, 0.6% dandelion, 0.6% witch hazel, 0.6% plum kernel, 0.6% alpine spirea , a mixture of 95.8% water for injection, ultrasonically stirred and soaked for 48 hours, filtered to remove insoluble impurities, sterilized in a packaging machine, subpackaged, and sealed to obtain a finished product.

[0050] When the finished product was used in mice w...

Embodiment 3

[0064] In terms of mass percentage, it will account for the total amount of 0.4% vitamin A, 0.5% vitamin E, 0.2% hydroxypropyl methylcellulose, 0.3% dandelion, 0.5% witch hazel, 0.3% plum kernel, 0.4% alpine floss A total of 7 raw materials of chrysanthemum are broken into powder and mixed evenly. Because vitamin A and E are not resistant to high temperature, they are sterilized by radiation; after the sealable stainless steel container is sterilized by high temperature, add water for injection accounting for 97.4% of the total. Control the temperature at 20 degrees Celsius, and then add sterilized 0.4% vitamin A, 0.5% vitamin E, 0.2% hydroxypropyl methylcellulose, 0.3% dandelion, 0.5% witch hazel, 0.3% plum kernel, The mixture of 0.4% Spiraea alpine and 97.4% water for injection is mixed evenly and then soaked for 72 hours, stirring continuously during the soaking process; filtering out insoluble impurities, completing sterilization in a packaging machine, subpackaging, and se...

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PUM

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Abstract

The invention relates to an eye drop and a preparation method thereof; in particular to an eye drop for alleviating dry eye syndrome and a preparation method thereof; it belongs to the field of medicine. The present invention uses vitamin A, vitamin E, hydroxypropyl methylcellulose, dandelion, witch hazel, plum kernel, and alpine spirea as raw materials, and through the synergistic effect between Chinese and Western medicines, obtains preservative-free, Do not contain antibiotics, use eye drops with few side effects and good effect. The preparation method of the invention is simple, the obtained eye drops have a long shelf life, and are convenient for industrialized production and application.

Description

[0001] Field [0002] The invention relates to an eye drop and a preparation method thereof; in particular to an eye drop for alleviating dry eye syndrome and a preparation method thereof; it belongs to the field of medicine. Background technique [0003] Eye drops are one of the most commonly used drugs for ophthalmic diseases. There are many kinds of them. For many eye diseases, eye drops have direct and quick therapeutic effects. Eye drops to relieve visual fatigue are one of them. With people's lifestyle and Changes in working conditions, a large number of Internet users, computer and mobile phone users, and car owners have increased the number of people with dry eye syndrome. Many people often experience dry eyes after facing computer screens, mobile phones or driving for a long time. Dry eye symptoms such as foreign body sensation, eye soreness, and blurred vision. In 2014, the family doctor conducted a "winter white-collar dry eye survey" online for white-collar worker...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/355A61K31/07A61K36/736A61K36/73A61K36/288A61K36/185A61P27/02
Inventor 黄瑞雪胡建安陈律任国峰杨飞丁萍黄德群李云鹏罗怀青陈鸿君刘晓英赵静李俞辰
Owner 杭州瑟尔弗生物科技有限公司
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