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Drug taste-masking agent and preparation method thereof

A preparation method and taste-masking agent technology, which can be applied in the direction of pharmaceutical formulations, medical preparations with non-active ingredients, etc., can solve problems such as bad smell and taste, complex ingredients, and large dosage, so as to improve the threshold of bitter taste and strong application value effect

Inactive Publication Date: 2015-03-04
WENZHOU FANGZHI BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the traditional Chinese medicine compound has insurmountable shortcomings, the ingredients are complex, the dosage is large, and most of them have a strong bad smell and taste, which seriously affects the patient's compliance.

Method used

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  • Drug taste-masking agent and preparation method thereof
  • Drug taste-masking agent and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A medicine taste-masking agent comprises the following components in parts by weight: 10 parts of Sichuan pepper, 10 parts of pepper and 10 parts of pepper.

[0020] A preparation method of a drug taste-masking agent, comprising the following steps:

[0021] (1) Get 10 parts of Chuanjiao, 10 parts of pepper, and 10 parts of capsicum in each part by weight;

[0022] (2) Active ingredients in Sichuan pepper, pepper, and capsicum in the extraction step (1);

[0023] (3) mixing the active ingredients obtained in step (2);

[0024] (4) Add appropriate amount of alcohol and water to the mixture in step (3) until the volume of the solution is 44 parts to obtain the drug taste-masking agent.

[0025] The medicine taste-masking agent can be formulated into a liquid medicine, and the medicine taste-masking agent is put into the mouth and swished for 1-5 seconds, spit out, and then drink the medicine.

Embodiment 2

[0027] A medicine taste-masking agent comprises the following components in parts by weight: 10 parts of Sichuan pepper, 10 parts of pepper and 10 parts of pepper.

[0028] A preparation method of a drug taste-masking agent, comprising the following steps:

[0029] (1) Get 10 parts of Chuanjiao, 10 parts of pepper, and 10 parts of capsicum in each part by weight;

[0030] (2) Active ingredients in Sichuan pepper, pepper, and capsicum in the extraction step (1);

[0031] (3) mixing the active ingredients obtained in step (2);

[0032] (4) Add appropriate amount of alcohol and water to the mixture in step (3) until the volume of the solution is 44 parts to obtain the drug taste-masking agent.

[0033] The drug taste-masking agent can be formulated into powder and attached to the outer layer of other drugs. When the drug is used, it will be disintegrated first, so that it can paralyze the oral cavity first, and then release other drug ingredients.

Embodiment 3

[0035] A medicinal taste-masking agent, comprising the following components in parts by weight: 30 parts of Sichuan pepper, 30 parts of pepper, and 30 parts of pepper.

[0036] A preparation method of a drug taste-masking agent, comprising the following steps:

[0037] (1) Get 30 parts of Chuanjiao, 30 parts of pepper, and 30 parts of capsicum in each part by weight;

[0038] (2) Active ingredients in Sichuan pepper, pepper, and capsicum in the extraction step (1);

[0039] (3) mixing the active ingredients obtained in step (2);

[0040] (4) Add appropriate amount of alcohol and water to the mixture in step (3) until the volume of the solution is 44 parts to obtain the drug taste-masking agent.

[0041] The medicine taste-masking agent can be formulated into a liquid medicine, and the medicine taste-masking agent is put into the mouth and swished for 1-5 seconds, spit out, and then drink the medicine.

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Abstract

The invention discloses a drug taste-masking agent which is characterized by comprising the following components in parts by weight: 1-30 parts of pericarpium zanthoxyli, 0-30 parts of pepper, and 0-30 parts of chili, wherein the effective ingredients in the components are water extracts or alcohol extracts. The taste-masking agent which has the local anesthesia function can temporarily palsy taste bud cells and improve the bitter taste threshold value, thereby achieving the taste masking purpose. The method can also be applicable to the taste-masking of other antibiotics, thereby having a higher application value.

Description

technical field [0001] In particular, the invention relates to a drug taste-masking agent and a preparation method thereof. Background technique [0002] The taste of medicines is an important factor affecting patients' compliance with taking medicines. Any preparation prescription, if it tastes good, will definitely be better than similar competing products, especially for pediatric medicines. The taste is easy for children to accept, which can greatly improve medication compliance. The traditional Chinese medicine compound has mild effects, few side effects, treats both symptoms and root causes, and focuses on conditioning. It is suitable for children's medicine, elderly conditioning medicine, and chronic disease long-term control conditioning medicine. But Chinese medicine compound has the shortcoming that is difficult to overcome, and composition is complicated, and dosage is big, and most have strong bad smell and taste, seriously affect patient's taking compliance. G...

Claims

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Application Information

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IPC IPC(8): A61K47/46
Inventor 张景亮李秀梅郭梦杰陈艳南杨丽
Owner WENZHOU FANGZHI BIOTECH
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