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Applications of Xinnaoxin capsule in preparation of medicines treating cerebral ischemia-reperfusion injury

A technology of cerebral ischemia reperfusion and capsules, which is applied in the field of medicine to achieve the effect of reducing behavioral scores and improving hemodynamic indicators

Inactive Publication Date: 2015-01-07
三普药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, its role in the treatment of cerebral ischemia-reperfusion injury has not been reported

Method used

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  • Applications of Xinnaoxin capsule in preparation of medicines treating cerebral ischemia-reperfusion injury
  • Applications of Xinnaoxin capsule in preparation of medicines treating cerebral ischemia-reperfusion injury
  • Applications of Xinnaoxin capsule in preparation of medicines treating cerebral ischemia-reperfusion injury

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] The Xinnaoxin capsule is prepared by mixing 3 parts by weight of rhodiola rosea, 5 parts of wolfberry and 3 parts of seabuckthorn.

Embodiment 2

[0015] The Xinnaoxin capsule is prepared by mixing 4 parts by weight of rhodiola rosea, 10 parts of wolfberry and 6 parts of seabuckthorn.

Embodiment 3

[0017] The Xinnaoxin capsule is prepared by mixing 5 parts by weight of rhodiola rosea, 12 parts of wolfberry and 8 parts of seabuckthorn.

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Abstract

Applications of a Xinnaoxin capsule in preparation of medicines treating cerebral ischemia-reperfusion injury are disclosed. The applications prove that: the capsule significantly reduces behavioral scores, a cerebral infarction rate, a NO content and NOS activity of rats, improves blood rheological dynamic indexes and relaxes NE-precontracted vessels in a concentration-dependent manner.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of Xinnaoxin Capsules in the preparation of medicines for treating cerebral ischemia-reperfusion injury. Background technique [0002] At present, ischemic cerebrovascular disease seriously affects the quality of human life. Cerebral ischemia, also known as cerebral infarction, is a type of disease caused by ischemia and hypoxia caused by cerebral blood flow disorder, resulting in localized ischemic necrosis or encephalomalacia, and cerebral ischemia-reperfusion injury is the cause of various Important pathophysiological mechanisms of cerebrovascular disease. Cerebral ischemia-reperfusion injury refers to the further aggravation of brain tissue damage after the blood perfusion of ischemic brain tissue is restored, and its mechanism has not been fully elucidated. In recent years, with the progress of shock treatment in clinical medicine and the promotion and a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61K9/48A61P9/10
CPCA61K36/41A61K9/48A61K36/185A61K36/815A61K2300/00
Inventor 史公权邹存生马俊仓吴留强夏彬牛蓉贺生玲李成秀
Owner 三普药业有限公司
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