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A traditional Chinese medicine extract for treating postpartum hypogalactia and its preparation method

A postpartum milk deficiency and extraction technology, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of non-targeted extraction process, low density of water extraction concentrate, and long production cycle. Achieve the effect of simple and easy extraction method, expand the applicable population, and meet market demand

Active Publication Date: 2017-11-21
NANJING ZHONGSHAN PHARMA CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] Ruquan granule has been approved for production. There are 15 domestic pharmaceutical companies with the approval number of Ruquan granule. The excipient is sucrose, which is too high in sucrose, which restricts the consumption of some patients who are not suitable for sucrose. The quality control items only have physical and chemical identification. Production During the process, the yield of different batches of ointment varies greatly; the density of the water extraction concentrate is low, the production cycle is long, and it is not easy to store; and the extraction process is not targeted and does not target the extraction of active ingredients of medicinal materials

Method used

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  • A traditional Chinese medicine extract for treating postpartum hypogalactia and its preparation method
  • A traditional Chinese medicine extract for treating postpartum hypogalactia and its preparation method
  • A traditional Chinese medicine extract for treating postpartum hypogalactia and its preparation method

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Effect test

Embodiment 1

[0181] Take 210kg of bulimia, 25kg of roasted pangolin, 90kg of trichosanthes, 150kg of angelica, 90kg of leaking reed, and 90kg of roasted licorice;

[0182] Take the prescription amount of Angelica sinensis and Leulu medicinal materials, add 8 times the concentration of the two medicinal materials, and heat and reflux with 60% ethanol to extract 3 times, each time for 1.5 hours, filter, combine the filtrates, and concentrate to a clear liquid with a relative density of 1.25 at 55 ° C. paste. Wang Buliuxing soaked 10 times the weight of the total medicinal materials in the prescription in water overnight, then added the above-mentioned dregs, trichosanthes, roasted pangolin, and roasted licorice, heated and refluxed for 3 times, each time for 2 hours, filtered, combined the filtrates, and concentrated to 50 A clear paste with a relative density of 1.25 under the condition of ℃. The clear extracts were combined twice and concentrated to an extract with a relative density of 1.3...

Embodiment 2

[0184] Take 210kg of bulimia, 25kg of roasted pangolin, 90kg of trichosanthes, 150kg of angelica, 90kg of leaking reed, and 90kg of roasted licorice;

[0185] Take the prescription amount of Angelica sinensis and Leulu medicinal materials, add 8 times the concentration of the two medicinal materials, and heat and reflux with 60% ethanol to extract 3 times, each time for 1.5 hours, filter, combine the filtrates, and concentrate to a clear liquid with a relative density of 1.25 at 55 ° C. paste. Wang Buliuxing soaked 10 times the weight of the total medicinal materials in the prescription in water overnight, then added the above-mentioned dregs, trichosanthes, roasted pangolin, and roasted licorice, heated and refluxed for 3 times, each time for 2 hours, filtered, combined the filtrates, and concentrated to 50 A clear paste with a relative density of 1.25 under the condition of ℃. Combine two clear extracts and concentrate to an extract with a relative density of 1.30-1.35 (45-...

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Abstract

The invention discloses a traditional Chinese medicine extract for treating postpartum hypogalactia and a preparation method of the traditional Chinese medicine extract. The traditional Chinese medicine extract is prepared by organically combining modes of alcohol extraction and water extraction. In the granulation process, cane sugar auxiliary materials in the conventional granulation process are replaced by steviosin, the application crowd range is widened, and standard, feasible and stable process parameters are provided for production.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine extract for treating postpartum hypogalactia and a preparation method thereof. Background technique [0002] Ruquan Granule is a commonly used Chinese patent medicine in gynecology, which was recorded in the seventh volume of "Prescriptions of Traditional Chinese Medicine" in the 1993 edition. Its prescription is composed of six medicinal materials such as wang buliu xing, pangolin (burned), angelica, leaking reed, trichosanthes, licorice (burned), etc. It has the effects of dredging menstruation, promoting blood circulation, and releasing breast milk. It is mainly used for liver depression and stagnation of qi in traditional Chinese medicine. Treatment of postpartum hypogalactia. [0003] Ruquan granule has been approved for production. There are 15 domestic pharmaceutical companies with the approval number of Ruqu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/484A61P15/14A61K35/36
Inventor 李静雅赵开军宋健王波竞存濮存海
Owner NANJING ZHONGSHAN PHARMA CO LTD
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