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Epoxystyrene-isoprene-styrene segmented copolymer medicine paster and preparation method thereof

A technology of epoxidizing styrene and styrene blocks, which is used in pharmaceutical formulations, medical preparations with non-active ingredients, and sheet transportation, etc., can solve the problems of easy occurrence of allergies, impact on sticking performance, poor adhesion ability, etc. , to avoid skin whitish allergy, improve the mixing amount of the drug, and enhance the adhesion performance.

Active Publication Date: 2014-09-03
浙江固特新材料科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] The SIS medical patch used in the past has the following disadvantages: poor adhesion, low polarity, poor air permeability, prone to allergies, and the production of sweat during use will also affect its posting performance

Method used

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  • Epoxystyrene-isoprene-styrene segmented copolymer medicine paster and preparation method thereof
  • Epoxystyrene-isoprene-styrene segmented copolymer medicine paster and preparation method thereof
  • Epoxystyrene-isoprene-styrene segmented copolymer medicine paster and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1: Preparation of epoxidized styrene-isoprene-styrene block copolymer medical patch

[0022] raw material:

[0023]

[0024]

[0025] (1) Preparation method:

[0026] Add part of naphthenic soybean oil to the reactor first, add ESIS and SEPS according to the weight ratio, then add antioxidant, heat to 160°C, start stirring, and pass nitrogen to replace the gas in the reactor.

[0027] After the ESIS is completely dissolved, add rosin pentaerythritol resin in proportion, and then add hydrogenated rosin resin after the temperature is constant.

[0028] Vacuum the kettle to keep it at -0.02mPa, stir for about 20 minutes to lower the temperature of the kettle, and use the internal cooling of the reactor to drop the temperature to 120°C before discharging.

[0029] (2) Product performance parameters:

[0030] Appearance: with light yellow transparent solid glue

[0031] Non-volatile matter: 100%

[0032] Purity: Heated to 160°C, all 100-mesh sieves pass...

Embodiment 2

[0039] Embodiment 2: Preparation of epoxidized styrene-isoprene-styrene block copolymer medical patch

[0040] raw material:

[0041]

[0042]

[0043] (4) Preparation method:

[0044] Add part of naphthenic soybean oil to the reactor first, add ESIS and SEPS according to the weight ratio, then add antioxidant, heat to 160°C, start stirring, and pass nitrogen to replace the gas in the reactor.

[0045] After the ESIS is completely dissolved, add rosin pentaerythritol resin in proportion, and then add hydrogenated rosin resin after the temperature is constant.

[0046] Vacuum the kettle to keep it at -0.05mPa, stir for about 20 minutes to lower the temperature of the kettle, and use the internal cooling of the reactor to drop the temperature to 120°C before discharging.

[0047] (5) Product performance parameters:

[0048] Appearance: with light yellow transparent solid glue

[0049] Non-volatile matter: 100%

[0050] Purity: Heated to 160°C, all 100-mesh sieves pass...

Embodiment 3

[0057] Embodiment 3: Preparation of epoxidized styrene-isoprene-styrene block copolymer medical patch

[0058] raw material:

[0059]

[0060]

[0061] (7) Preparation method:

[0062] Add part of naphthenic soybean oil to the reactor first, add ESIS and SEPS according to the weight ratio, then add antioxidant, heat to 160°C, start stirring, and pass nitrogen to replace the gas in the reactor.

[0063] After the ESIS is completely dissolved, add rosin pentaerythritol resin in proportion, and then add hydrogenated rosin resin after the temperature is constant.

[0064] Vacuum the kettle to keep it at -0.03mPa, stir for about 20 minutes to lower the temperature of the kettle, and use the internal cooling of the reactor to drop the temperature to 120°C before discharging.

[0065] (8) Product performance parameters:

[0066] Appearance: with light yellow transparent solid glue

[0067] Non-volatile matter: 100%

[0068] Purity: Heated to 160°C, all 100-mesh sieves pass...

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Abstract

The invention discloses an epoxystyrene-isoprene-styrene segmented copolymer (SIS) medicine paster and a preparation method thereof, and aims to provide the epoxystyrene-isoprene-styrene segmented copolymer (SIS) medicine paster with good adhesion ability, good air permeability and high stability and the preparation method thereof; the epoxystyrene-isoprene-styrene segmented copolymer (SIS) medicine paster includes 20-35 parts of epoxystyrene-isoprene-styrene segmented copolymer (ESIS), 10-18 parts of hydrogenatedstyrene-isoprene-styrene segmented copolymer(SEPS), 15-25 parts of epoxy soybean oil, 8-15 parts of hydroxy terminated liquid polybutadiene, 15-25 parts of hydrogenated rosin resin, 10-20 parts of rosin pentaerythritol ester and 0.2 part of an antioxidant, and the epoxystyrene-isoprene-styrene segmented copolymer (SIS) medicine paster has the advantages of strong adhesion, good air permeability, good flexibility, more stable performance, and the like.

Description

technical field [0001] The invention relates to a medical patch and a preparation method thereof, in particular to an epoxidized styrene-isoprene-styrene block copolymer (SIS) medical patch and a preparation method thereof. Background technique [0002] The SIS medical patch used in the past has the following disadvantages: poor adhesion, low polarity, poor air permeability, prone to allergies, and the production of sweat during use will also affect its posting performance. Contents of the invention [0003] The purpose of the present invention is to provide a kind of adhesion ability good in order to solve the deficiency of above-mentioned technology, gas permeability is good, the epoxidized styrene-isoprene-styrene block copolymer medical patch and its high stability Preparation. [0004] In order to achieve the above object, a kind of epoxidized styrene-isoprene-styrene block copolymer medical patch designed by the present invention comprises epoxy styrene-isoprene-sty...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/70A61K47/32A61K47/34A61K47/08A61K47/14
Inventor 邵宝有陈慧李光鹏陈惠娟
Owner 浙江固特新材料科技股份有限公司
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