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Traditional Chinese medicine for prevention and treatment of broiler chicken colibacillosis

A technology of traditional Chinese medicine and broiler, applied in antibacterial drugs, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of immune failure, rare, unsatisfactory immune effect of bacterin, and achieve edible safety and effect. Significant, less resistant effects

Inactive Publication Date: 2014-02-19
王双山
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, immunization is used to prevent colibacillosis in broilers. Since there are many serotypes of E. coli, the immunization effect of the vaccine is not ideal, which often leads to immunization failure.
In recent years, although traditional Chinese medicine has been used in the treatment of colibacillosis in chickens, there are still few traditional Chinese medicine prescriptions dedicated to the prevention and treatment of colibacillosis in broilers.

Method used

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  • Traditional Chinese medicine for prevention and treatment of broiler chicken colibacillosis
  • Traditional Chinese medicine for prevention and treatment of broiler chicken colibacillosis
  • Traditional Chinese medicine for prevention and treatment of broiler chicken colibacillosis

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Effect test

Embodiment 1

[0043] Embodiment 1 Chinese medicine prescription of the present invention is to artificially infected broiler colibacillosis treatment test

[0044] Experimental Materials

[0045] Chinese herbal medicines: Coptis chinensis, Pulsatilla chinensis, Scutellaria baicalensis, Daqingye, pomegranate peel, black plum, myrobalan, astragalus, hawthorn, divine comedy, turmeric, and woody fragrance were all purchased from the Affiliated Hospital of Anyang School of Traditional Chinese Medicine. The above-mentioned prescription Chinese medicine complies with the relevant regulations of "Chinese Veterinary Pharmacopoeia".

[0046] Antibiotics: 30% Florfenicol Injection, specification 10mg / ml, produced by Shandong Qilu Pharmaceutical Factory. A 10-fold dilution was performed when used.

[0047] Culture medium: Broth medium was prepared according to the method of relevant references, and MacConkey agar medium was commercially available.

[0048] Bacterial strain: Escherichia coli isolated...

Embodiment 2

[0064] Embodiment 2 Chinese medicine prescription of the present invention is to artificially infected broiler colibacillosis preventive test

[0065] Experimental Materials

[0066] Chinese herbal medicines: Coptis chinensis, Pulsatilla chinensis, Scutellaria baicalensis, Daqingye, pomegranate peel, black plum, myrobalan, astragalus, hawthorn, divine comedy, turmeric, and woody fragrance were all purchased from the Affiliated Hospital of Anyang School of Traditional Chinese Medicine. The above-mentioned prescription Chinese medicine complies with the relevant regulations of "Chinese Veterinary Pharmacopoeia".

[0067] Antibiotics: 30% Florfenicol Injection, specification 10mg / ml, produced by Shandong Qilu Pharmaceutical Factory. A 10-fold dilution was performed when used.

[0068] Culture medium: Broth medium was prepared according to the method of relevant references, and MacConkey agar medium was commercially available.

[0069] Bacterial strain: Escherichia coli isolate...

Embodiment 3

[0085] Embodiment 3 Chinese medicine preparation of the present invention is to clinical disease broiler chicken treatment experiment

[0086] In broiler chicken farms in Anyang, Puyang, Hebi and other cities in the northern part of Henan Province, clinical trials of colibacillosis were carried out on broiler chickens with the developed traditional Chinese medicine prescription.

[0087] Preparation of traditional Chinese medicine prescription: Weigh Coptidis 15, Pulsatilla 20, Scutellaria baicalensis 15, Daqingye 20, Pomegranate peel 12, Black plum 10, Myrobalan 15, Astragalus 12, Hawthorn 20, Divine Comedy 10, Curcuma 20 and Muxiang according to parts by weight. 15. Add 8 times the amount of distilled water, soak for 35 minutes, decoct, boil, decoct with slow fire for 1 hour, and filter with 4 layers of gauze; add appropriate amount of boiling distilled water to the dregs, decoct for 30 minutes, and filter; combine the two medicines and concentrate them with a rotary evaporat...

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Abstract

The invention discloses a traditional Chinese medicine for prevention and treatment of broiler chicken colibacillosis. The traditional Chinese medicine is composed of the following drugs in parts by weight: 15-20 parts of coptis chinensis, 20-24 parts of radix pulsatilla, 15-20 parts of radix scutellariae, 20-28 parts of folium isatidis, 12-14 parts of pericarpium granati, 10-12 parts of fructus mume, 15-20 parts of fructus chebulae, 12-15 parts of radix astragali, 20-30 parts of hawthorn, 10-20 parts of medicated leaven, 20-22 parts of radix curcumae, and 15-18 parts of radix aucklandiae. The prescription is developed according to Chinese veterinarian overall concepts and a dialectic diagnosis and treatment theory, has heat-clearing, detoxifying, anti-bacterial, anti-inflammatory, intestine-astringing and antidiarrheal efficacies, and has remarkable effect on prevention and treatment of broiler chicken colibacillosis. Popularization application indicates that clinical treatment of broiler chicken colibacillosis has the cure rate of 84.5%. Preventive medication is implemented on broiler chicken farms, the broiler chicken colibacillosis death rate is decreased from 9.0% to 1.89%; the prescription has no residue, does not easily produce drug resistance, and allows meat products to be safe to eat; and the traditional Chinese medicine prescription is simple in preparing method, easy to use, and beneficial for popularization.

Description

technical field [0001] The invention relates to a traditional Chinese medicine for chickens, in particular to a traditional Chinese medicine for preventing colibacillosis of broilers. Background technique [0002] Broiler colibacillosis is one of the important broiler chicken diseases caused by different serotypes of Escherichia coli. The main clinical manifestations are sepsis, fibrinous air sacculitis, perihepatitis, pericarditis and peritonitis. Chickens of all breeds and ages can be infected, but broiler chickens are the most susceptible. The disease is not only the primary disease of broiler chickens, but also the secondary disease in the occurrence of various diseases such as Newcastle disease, avian influenza, and chronic respiratory diseases. resulting in high morbidity and mortality. [0003] In recent years, broiler breeding in northern Henan has developed very rapidly and the degree of intensification has continued to increase. It has become an important broiler...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P31/04
Inventor 王双山申海燕郭玉萍石卫峰侯海鹏王建丽于东丽
Owner 王双山
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