Automatic judgment and control for eluant receiving of buckeye extract
An elution process and automatic judgment technology, applied in chemical instruments and methods, solid adsorbent liquid separation, color/spectral characteristic measurement, etc., can solve problems such as poor product quality uniformity, avoid losses and waste, and save labor costs. , to ensure the effect of quality uniformity and stability
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[0041] Example 1 Rapid Judgment and Automatic Control of the Starting Point and End Point of Collecting the Eluate in the Purification Process of the Macroporous Resin of the Salsa Seed Extract
[0042] Salazi: place of origin: Hanzhong, Shaanxi, storage number: YC1100301;
[0043] Near-infrared spectrometer: Matrix-F, German Bruker Spectroscopy Instrument Co., Ltd.;
[0044] HPLC chromatograph: 1200Series, Agilent Technologies Co., Ltd.;
[0045] Aescin sodium reference substance: batch number 200402, source: China Institute for the Control of Pharmaceutical and Biological Products.
[0046] (1) Construction of near-infrared on-line detection system
[0047] The macroporous resin near-infrared online detection system mainly includes: (1) resin column, (2) flow regulating valve, (3) flow cell, (4) sampling valve, (5) optical fiber, (6) near-infrared spectrometer, (7) ) computer, (8) DCS control system. Among them, the macroporous resin column bypass is equipped with a flow...
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