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Application of Chinese medicine composition in preparing medicines for treating pulmonary heart disease

A technology for pulmonary heart disease and a composition, which is applied in the application field of traditional Chinese medicine compositions in the preparation of medicines for treating pulmonary heart disease, and achieves the effects of no adverse reactions, definite curative effect, and obvious adverse reactions.

Active Publication Date: 2014-09-24
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no special treatment for this disease. The acute exacerbation period is mainly symptomatic treatment, and the main purpose of the remission period is to reduce or avoid the occurrence of the acute exacerbation period.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Embodiment 1: the preparation of medicine capsule of the present invention

[0040] prescription:

[0041] Astragalus 450g Aconite 112.5g Ginseng 225g Salvia 225g Tinglizi 150g Persimmon bark 180g Alisma 225g Safflower 90g Polygonatum 75g Tangerine peel 75g Guizhi 90g

[0042]Preparation:

[0043] (1) Reflux extract astragalus, Tinglizi, Alisma, ginseng, and Xiangjia bark according to the above prescription plus 8 times the amount of 70% ethanol for 2 times, the first time for 3 hours, and the second time for 2 hours, combine the extracts, filter After filtration, the filtrate was decompressed to recover ethanol, concentrated to 60°C to measure the clear paste with a relative density of 1.25-1.30, and set aside;

[0044] (2) Distill cinnamon sticks and tangerine peel to extract volatile oil according to the ratio; filter the aqueous solution after oil extraction, and set aside, add 8 times the amount of water to the residue and decoct for 1 hour, filter, combine the...

Embodiment 2

[0048] Embodiment 2: the preparation of active ingredient

[0049] prescription:

[0050] Astragalus 450g Aconite 112.5g Ginseng 225g Salvia 225g Tinglizi 150g Persimmon bark 180g Alisma 225g Safflower 90g Polygonatum 75g Tangerine peel 75g Guizhi 90g

[0051] Preparation:

[0052] (1) Extract astragalus, Tinglizi, Alisma, ginseng or Codonopsis pilosula, Xiangjia bark or Nanwujia bark with 70% ethanol, filter, and concentrate to a clear liquid with a relative density of 1.25-1.30 when measured at 60°C. ointment;

[0053] (2) Extract the volatile oil of cassia twig and tangerine peel; filter the aqueous solution after oil extraction, collect the aqueous filtrate, add water and decoct the residue for 1 hour, filter, and combine the aqueous solutions to obtain the water extract after oil extraction;

[0054] (3) Aconite, Danshen, Yuzhu, and safflower are decocted twice with water, combined with the extract, filtered; combined with the water extract obtained in step (2), conc...

Embodiment 3

[0056] Embodiment 3: the preparation of pharmaceutical tablet of the present invention

[0057] prescription:

[0058] Astragalus 150g Aconite 40g Ginseng 225g Salvia 225g Tinglizi 50g Xiangjiapi 180g Alisma 75g Polygonatum 75g Guizhi 30g Safflower 90g Chenpi 25g

[0059] Preparation:

[0060] (1) Weigh Astragalus membranaceus, Tinglizi, Alisma, ginseng, and Xiangjia bark according to the proportion of the prescription, add 8 times the amount of 70% ethanol to reflux and extract twice, the first time is 3 hours, the second time is 2 hours, and the extracts are combined , filtered, and the filtrate was decompressed to recover ethanol, concentrated to a clear paste with a relative density of 1.25-1.30 when thermally measured at 60°C, and set aside;

[0061] (2) Distill and extract volatile oils from cinnamon sticks and tangerine peel according to the prescription amount; filter the aqueous solution after oil extraction, and set aside, add 8 times the amount of water to the r...

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Abstract

The invention discloses an application of a traditional Chinese medicine composition in preparing medicine for treating cor pulmonale. The traditional Chinese medicine composition of the present invention is composed of 11 traditional Chinese medicines such as astragalus, ginseng, and salvia miltiorrhiza. . Experimental studies have confirmed that the traditional Chinese medicine composition of the invention can effectively treat cor pulmonale.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to the application of a traditional Chinese medicine composition in the preparation of medicines for treating cor pulmonale. Background technique [0002] Chronic cor pulmonale, referred to as chronic cor pulmonale, is caused by chronic lesions in the lung tissue, pulmonary vessels or thorax, resulting in abnormal lung tissue structure and (or) function, resulting in increased pulmonary vascular resistance, increased pulmonary artery pressure, and dilated right ventricle or ( and) hypertrophy, heart disease with or without right heart failure, and exclude congenital heart disease and left heart disease. Chronic cor pulmonale is a common disease of the respiratory system in my country. Clinically, in addition to the various symptoms and signs of the original lung and chest diseases, it is mainly the gradual appearance of signs of lung and heart failur...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8969A61P11/00A61P9/00
Inventor 张喜芬王永王猛马静杨超何慧民刘晓燕秦拢
Owner HEBEI YILING MEDICINE INST
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