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Chinese rhubarb-baical skullcap root-amur corktree bark itching-relieving liniment and preparation method thereof

A technology for relieving itching and treats, applied in pharmaceutical formulas, medical preparations containing active ingredients, plant raw materials, etc., can solve problems such as adverse reactions and discomfort, and achieve the effect of low price and safe use

Inactive Publication Date: 2012-11-28
SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Commonly used external medicines for the treatment of eczema and dermatitis include topical glucocorticoid paste or 25% to 40% zinc oxide oil or paste (generally made by hospitals); most of the products on the market are ointments, and long-term use of hormone ointment is easy. Produce various adverse reactions, and it is not suitable for those with exudation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] The composition and dosage of raw materials are: Sophora flavescens 25g, Rhubarb 25g, Scutellaria baicalensis 25g, Cortex Phellodendri 25g.

[0012] Mix and pulverize the above-mentioned raw materials into fine powder according to the above-mentioned parts by weight, pass through an 80-mesh sieve, and mix well; add 5 g of fully swollen sodium carboxymethyl cellulose, add 10 g of melted phenol, stir well, add water Adjust the total amount to 1000ml.

[0013] The using method of liniment described in the present embodiment is as follows:

[0014] The liniment that adopts above-mentioned preparation method to make is divided into bottles by 100 ml / bottle. Apply topically, once a night, shake well before use. 2 weeks is a course of treatment.

Embodiment 2

[0015] Embodiment 2: The difference between this embodiment and Embodiment 1 is the difference in the composition of the crude drug. This embodiment is aimed at patients with acne symptoms.

[0016] Composition of raw materials: Sophora flavescens 25g, rhubarb 25g, skullcap baicalensis 25g, cork phellodendron 25g, hedyotis 30g, dandelion 30g. 2 weeks is a course of treatment.

[0017] Symptoms of acne: facial pimples, blackheads, pustules, nodules, and cysts in severe cases.

[0018] The following is a report of clinical application of the present embodiment and the comparison group: twenty patients in each group.

[0019] group Treatment time (weeks) Clinically cured (example) Get better (example) unhealed (example) Retinoic acid group 2 1 3 16 Retinoic acid group 4 4 4 12 Example set 2 0 6 14 Example set 4 8 8 4 Example two groups 2 4 6 10 Example two groups 4 12 4 4

[0020] Referring to the "Diagno...

Embodiment 3

[0025] Embodiment 3: The difference between this embodiment and Embodiment 1 is the difference in the composition of the crude drug. This embodiment is aimed at patients with rosacea symptoms.

[0026] Composition of raw materials: Sophora flavescens 25g, rhubarb 25g, scutellaria baicalensis 25g, Phellodendron cortex 25g, Shengdi 30, Morus alba 30. 2 weeks is a course of treatment.

[0027] Symptoms of rosacea: nasal flushing, obvious when emotional, papules, pustules, telangiectasia, skin hypertrophy, and finally rhinophyma.

[0028] The following is a report of clinical application of the present embodiment and the comparison group: twenty patients in each group.

[0029] group Treatment time (weeks) Clinically cured (example) Get better (example) unhealed (example) Compound sulfur lotion or 5% sulfur ointment 2 0 2 18 Compound sulfur lotion or 5% sulfur ointment 4 2 6 12 Example set 2 0 8 12 Example set 4 4 12 4 Exam...

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PUM

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Abstract

The invention relates to an external pharmaceutical composition liniment and a preparation method thereof and especially relates to a Chinese rhubarb-baical skullcap root-amur corktree bark itching-relieving liniment and a preparation method thereof. Based on 1000 parts by weight of the Chinese rhubarb-baical skullcap root-amur corktree bark itching-relieving liniment, the Chinese rhubarb-baical skullcap root-amur corktree bark itching-relieving liniment comprises 20 to 30 parts by weight of lightyellow sophora root, 20 to 30 parts by weight of Chinese rhubarb, 20 to 30 parts by weight of baical skullcap root, 20 to 30 parts by weight of amur corktree bark, 10 to 15 parts by weight of gentiana scabra bunge and 20 to 30 parts by weight of raw cape jasmine fruit. The preparation method comprises the following steps of mixing the above traditional Chinese medicines according to the weight part ratio, crushing the mixture into fine powder, sieving, uniformly mixing, adding 3 to 10 parts by weight of completely swelled sodium carboxymethylcellulose into the mixed fine powder, adding 5 to 15 parts by weight of melted phenol into the mixture obtained by the previous step, uniformly stirring, and adding the balance water into the mixture obtained by the previous step. The Chinese rhubarb-baical skullcap root-amur corktree bark itching-relieving liniment has the effects of clearing away heat and toxins, inducing astringency and relieving itching, treating acute-stage skin diseases such as red and swollen skin, hot itching and exudation caused by obstruction of evil syndromes, has functions of heating removal and convergence, is suitable for treating various acute-stage skin damages with a small amount of exudation, is prepared from pure traditional Chinese medicines, is safe in use, has no irritation, can be used for a long time, and has a low cost.

Description

[0001] technical field [0002] The invention relates to a liniment for external use of a pharmaceutical composition and a preparation method thereof, in particular to a sanhuang antipruritic liniment and a preparation method thereof. Background technique [0003] At present, for acne, rosacea, furunculosis, eczema, dermatitis (acute phase with mild exudation), herpes zoster (acute phase with blisters), the following drugs are usually used for treatment, such as Commonly used external medicines for treating acne include: 1. Retinoic acid: such as retinoic acid cream (15-20 yuan), retinoic acid gel (35 yuan), isotretinoin gel (more than 50 yuan), etc. , but mild irritation (such as local flushing, desquamation or burning sensation) may occur after administration. 2. Antibiotics: such as 1% to 2% erythromycin ointment (1 to 2 yuan), lincomycin VB6 ointment (about 30 yuan), suitable for infected rashes. The effects of these two types of drugs are limited, and some patients fe...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P17/04
Inventor 顾乃芳蔡希吴怡峰傅燕华卞青
Owner SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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