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Chinese medicine composition for reducing blood fat

A composition and blood lipid-lowering technology are applied in the directions of drug combination, pharmaceutical formula, plant raw materials, etc., and can solve the problems of unclear curative effect, high price, and unfavorable promotion and application.

Active Publication Date: 2011-05-18
ZHEJIANG UNIV +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there are many Chinese patent medicines for the treatment of hyperlipidemia, some of which have too large prescriptions and unclear curative effects, and some are quite expensive due to the use of precious medicinal materials in the prescriptions
These make it unfavorable to promote the price application

Method used

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  • Chinese medicine composition for reducing blood fat

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Experimental program
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Effect test

Embodiment 1

[0012] The preparation method of embodiment 1 Chinese medicine composition

[0013] Take 2000g of Radix Paeoniae Rubra, 500g of Citrus aurantii and 500g of Allium scallops, combine them, add 30000ml of water to reflux and extract twice, each time for 1h, combine the extracts, filter, concentrate under reduced pressure, and dry to obtain the product.

[0014]

Embodiment 2

[0015] The preparation method of embodiment 2 Chinese medicine composition

[0016] Take 3000g of Radix Paeoniae Rubra, 2000g of Fructus Aurantii, and 1000g of Allium scallops, combine them and add water to reflux to extract 3 times, each time for 1 hour, and use 8 times the amount of water each time, combine the extracts, filter, apply macroporous resin to the filtrate, and rinse with water after loading , discarded, and then eluted with 50%-95% ethanol solution, the eluate was concentrated under reduced pressure, dried, and obtained.

[0017]

Embodiment 3

[0018] The preparation method of embodiment 3 Chinese medicine composition

[0019] (1) Take 2000g of Radix Paeoniae Rubra, extract it twice with water, each time for 1 hour, the first time with 10 times the amount of solvent, and the second time with 8 times the amount of solvent. The combined extracts were centrifuged and loaded on D101 resin. After loading, 4BV was washed with water, and then 4BV was eluted with 40% ethanol. The 40% ethanol eluate was collected, concentrated, and dried.

[0020] (2) Take 600g of Fructus Fructus Fructus Fructus Aurantii, use alkaline water with pH=11 as the solvent, extract 3 times, each time for 1 hour, and the amount of solvent used is 10 times the amount. The extracts were combined, filtered and loaded on D101 resin. After sample loading, wash 4BV with water, then elute 4BV with 50% ethanol, collect the 50% ethanol eluate, concentrate, and dry.

[0021] (3) Take 600g of Allium scallions, add 10 times the amount of water to extract the v...

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Abstract

The invention provides a Chinese medicine composition for reducing blood fat, which comprises the following Chinese medicinal herbs in parts by weight: 12-25 parts of root of common peony, 3-15 parts of fruit of trifoliate orange and 3-15 parts of allium macrostemon. The composition has better blood fat reducing efficacy and has the advantages of simple prescription and low cost. According to the extraction, separation and preparation technology of the modern Chinese medicine, the Chinese medicine composition can be prepared into a reasonable preparation.

Description

technical field [0001] The invention belongs to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for lowering blood fat. Background technique [0002] With the continuous improvement of people's living standards, the incidence of hyperlipidemia is on the rise, and hyperlipidemia is the cause of coronary atherosclerotic heart disease (coronary heart disease), arteriosclerosis, fatty liver, diabetes, obesity important factors of disease. Therefore, it is of great practical significance to find efficient and non-toxic blood lipid-lowering drugs. [0003] Lipoproteins refer to proteins combined with lipids, including very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL). The lipid composition of different lipoproteins is mainly quantitative different, less qualitatively different. 80% to 90% of the chemical composition of very low-density lipoprotein is triacylglycerol, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61P3/06
Inventor 程翼宇张伯礼叶正良
Owner ZHEJIANG UNIV
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