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Application of patchouli oil to preparing drugs for treating bacterial infectious diseases

A technology for infectious diseases and bacterial infections, used in antibacterial drugs, resistance to vector-borne diseases, pharmaceutical formulations, etc.

Inactive Publication Date: 2011-05-18
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, there are no reports on the use of patchouli oil (Pogostemon cablin (Blanco) Benth.) and Agastache rugosa (Fisch.et Mey) O.ktze.) to effectively treat bacterial infectious diseases caused by Escherichia coli

Method used

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  • Application of patchouli oil to preparing drugs for treating bacterial infectious diseases
  • Application of patchouli oil to preparing drugs for treating bacterial infectious diseases
  • Application of patchouli oil to preparing drugs for treating bacterial infectious diseases

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The preparation of embodiment 1 Huoxiang oil of the present invention

[0022] Take patchouli medicinal material (Pogostemon cablin (Blanco) Benth.), crush through a 20-40 mesh sieve, add 10-14 times the weight of distilled water, soak for 1-5 hours, and extract by steam distillation for 2-6 hours. Promptly get the Huoxiang oil of the present invention, wherein contains bocicol (C 15 h 26 O) shall not be lower than 26.0%.

Embodiment 2

[0023] The preparation of embodiment 2 Huoxiang oil of the present invention

[0024] Take Agastache rugosa (Fisch.Et Mey.) O.Ktze.), crush through a 20-40 mesh sieve, add 10-14 times the weight of distilled water, soak for 1-5 hours, and extract by steam distillation After 2-6 hours, Huoxiang oil of the present invention was obtained.

[0025] Huoxiang oil of the present invention also can extract according to Pharmacopoeia (2005 edition) appendix XD volatile oil determination method, also can adopt organic solvent extraction, supercritical CO 2 extraction and other existing techniques, or obtain by purchasing commercially available products. Embodiments 1 and 2 should not be interpreted as limiting the scope of protection of the present invention to the preparation method of Huoxiang oil of the present invention. All modifications, replacements and changes based on the above-mentioned technical ideas and utilizing common technical knowledge and conventional means in the art...

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Abstract

The invention provides application of patchouli oil to preparing drugs for treating bacterial infectious diseases. The invention also provides a drug composition for treating the bacterial infectious diseases. The drug of the invention has stronger internal and external antibacterial activity on resistant strains in gram positive bacteria and gram negative bacteria and escherichia coli, can effectively treat infectious diseases caused by the resistant strains in clinical gram positive bacteria and gram negative bacteria as well as the resistant strains and sensitive strains in the escherichia coli, and provides a new drug selection for clinic.

Description

technical field [0001] The present invention relates to the application of Huoxiang oil in the preparation of medicines for the treatment of bacterial infectious diseases, specifically, the use of the preparation of medicines for the treatment of infectious diseases including Gram-positive bacteria and Gram-negative drug-resistant bacteria, and large intestine Use in medicine for Escherichia infectious diseases. Background technique [0002] Bacterial infectious disease is one of the common infectious diseases at present. It is an infectious disease caused by bacteria invading some parts of the human body under certain conditions. Inflammation, appendicitis, pneumonia, neonatal meningitis, etc.; can also invade the blood and enter the body circulation, thereby causing host fever, toxemia, sepsis, pericarditis, perihepatitis, air sac inflammation, etc., and even shock death. [0003] At present, antibiotics are mostly used for the treatment of bacterial infectious diseases. ...

Claims

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Application Information

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IPC IPC(8): A61K36/532A61K36/53A61P31/04C11B1/04C11B1/16
CPCY02A50/30
Inventor 彭成代敏万峰
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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