Device for collecting and separating body fluid sample used for cell examination and method therefor

Abstract

The invention relates to a device for collecting and separating a body fluid sample used for cell examination and a method therefor. The device comprises a sample collection container and a cell smear device, wherein the sample collection container comprises a container body with an opening at the top part; a lateral liquid discharge hole provided with a liquid discharge hole switch is arranged at the lower part of the side wall of the container body; the bottom of the container body is of the V shape or the turbination; and a T-shaped collection pipe is arranged at the bottom of the V shape or the turbination. The method comprises: adding various body fluid samples into the container body for resting, so that the visible components such as cells and the like in the body fluid samples canbe naturally precipitated into the collection pipe, and the liquid supernatant of the body fluid can be discharged by the liquid discharge hole; and then taking down the collection pipe and directly fixing the collection pipe on the cell smear device, and adopting a general centrifugation smear machine to prepare a cell smear directly. The device and the method can successfully collect large amount of the visible components such as cells, sediment and the like in the body fluid sample, can achieve the aim of obviously improving the relevance ratio of positive cells and can be widely used for the cytological examination of various body fluid samples.

Description

technical field [0001] The invention belongs to the cytological examination apparatus in medical equipment in the medical field, and particularly relates to a body fluid that can be used in clinical body fluid samples (pleural effusion, ascites, urine, cerebrospinal fluid, drainage fluid) and cell culture fluid and bacterial culture fluid for cell inspection Sample collection, separation devices and methods. Background technique [0002] Cytological examination of body fluid samples such as pleural effusion, ascites, urine, cerebrospinal fluid, and various body cavity drainage fluids is an important part of daily medical work, especially for cytopathologists. Whether the formed components in the above-mentioned body fluid samples can be effectively collected and separated, especially various exfoliated cells is directly related to the quality of cell smears, cytopathological diagnosis and positive detection rate, and also determines whether patients can be diagnosed in time ...

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Problems solved by technology

[0003] However, in daily medical practice, there are generally many kinds of body cavity drainage fluids, especially bodily fluid samples such as pleural effusion, ascites, and urine, which are huge in volume, often ranging from hundreds of milliliters to thousands of milliliters. Therefore, if There is undoubtedly a huge risk of misdiagnosis in taking a small number of samples for cytological examination. However, due to the lack of suitable equipment at present, it is necessary to test all body fluid samples (such as hundreds of milliliters of pleural effusion, ascites, or thousands of milliliters of 24-hour urine). The collection and separation of exfoliated cells in samples) is a cumbersome and difficult to achieve satisfactory results. At present, the following methods are generally used: (1) Borrow a larger container (such as an infusion bottle) and pour it out after standing still Supernatant, and then absorb the liquid smear at the bottom of the container for cytological examination; (2) Use a large-capacity centrifuge tube to centrifuge the above-mentioned body fluid samples in batches and in batches, collect them together, and then smear for cytological examination; Obviously, the above method is very cumbersome, and it may still cause missed diagnosis because some cells adhere to the tube wall, and there is also a risk of contamination

[0004] It can be seen that the existing methods for cytological examination of body fluid samples have the disadvantages of cumbersome work, easy pollution, low efficiency, and easy missed diagnosis.

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