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Sugarless south isatis root granules and preparation method thereof

A technology of Nanlangen and sugar-free type, which is applied in the direction of medical formulas, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problem that it is not suitable for diabetic patients and patients with hyperglycemia, and achieve reduction Sweetness, reducing the amount of excipients, and saving costs

Inactive Publication Date: 2009-12-23
肖军平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing Nanbanlangen effervescent granules need to add sucrose, essence, etc. during the production process. They are sugar-containing drugs and are not suitable for diabetics and hyperglycemic patients.

Method used

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  • Sugarless south isatis root granules and preparation method thereof
  • Sugarless south isatis root granules and preparation method thereof
  • Sugarless south isatis root granules and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0053] The production method that above-mentioned each component is made into medicine of the present invention is:

[0054] Weigh Radix Isatidis and Folium Isatidis and add 6 times the amount of water to decoct twice, each time for 2 hours, filter through a 200-mesh sieve, combine the decoction, and use the filtrate for later use; take the above decoction and put it in a recovery concentration tank, reduce Pressure (vacuum degree is -0.03Mpa) concentrated to the extract with a relative density of 1.10 (measured at 60°C), add 2 times the amount of 70% ethanol, mix well, let stand for 20 hours, filter, and the filtrate is set aside; take the above alcohol precipitation Liquid, recover ethanol under reduced pressure and concentrate to the extract with a relative density of 1.28 (70°C); take the above extract, add dextrin and stevia, mix, granulate, dry at about 70°C until the water content is about 8%, and the whole After granulation, continue to dry at 80°C until the water cont...

Embodiment 2

[0056] The production method that above-mentioned each component is made into medicine of the present invention is:

[0057] The production method of making the medicine of the present invention is: first take by weighing Radix Isatidis and Folium Folium, add 8 times the amount of water and decoct twice, each time for 2.5 hours, filter with a 210 mesh sieve, merge the decoction, and the filtrate is for subsequent use; The decoction is placed in a reclaiming concentration tank, concentrated under reduced pressure (vacuum degree is -0.05Mpa) to an extract with a relative density of 1.15 (measured at 70°C), adding 3 times the amount of 70% ethanol, mixing, and standing for 24 hours. Filtrate the filtrate for later use; take the above alcohol precipitation solution, recover ethanol under reduced pressure and concentrate it to an extract with a relative density of 1.30 (70°C); take the above extract, add dextrin and stevia, mix, granulate, and heat at 70°C Dry around until the wate...

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PUM

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Abstract

The invention relates to sugarless south isatis root granules and a preparation method thereof. The sugarless south isatis root granules are prepared from south isatis root, dyer woad leaf, amylin and steviosin and are prepared by decoction, concentration, standing, recovery, and drying in proportion. The method changes the original sugar granules into sugarless granules, uses the amylin to replace cane sugar, and adds a small amount of the steviosin to adjust the mouthfeel, reduces the saccharinity of the original sugar granules, and reduces the dosage of auxiliary materials and the cane sugar in the preparation. The applied dosage of the sugarless granules is not changed compared with that of the original sugar granules, so that the sugarless south isatis root granules can adapt to more patients.

Description

technical field [0001] The invention relates to a Chinese patent medicine prepared from Chinese herbal medicines, in particular to a Nanbanlangen granule. Background technique [0002] Cold and sore throat are common and frequent diseases. The compound Nanbanlangen effervescent granules have been widely used. At present, Nanbanlangen and Folium Isatidis are mainly used as main raw materials to make Nanbanlangen. Nanbanlangen mainly contains indoles, Sterols, pentacyclic triterpenes, amino acid compounds, etc. Modern pharmacological studies have shown that Nanbanlangen has the effects of clearing heat and detoxifying, cooling blood and relieving throat, anti-tumor, anti-bacterial and anti-inflammatory, and protecting the liver. Folium Folium mainly contains indole compounds such as indigo, indirubin, isadin B, etc. It has the functions of clearing heat and detoxifying, cooling blood and eliminating spots, and resisting endotoxin. Sore throat erysipelas, carbuncle. The exis...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/315A61K36/19A61K9/16A61K47/36A61P11/00A61P11/04A61P31/12A61P1/16A61P29/00
Inventor 肖军平
Owner 肖军平
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