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Cynomolgus monkey magnetic resonance scanning method

A magnetic resonance scanning, cynomolgus monkey technology, applied in medical science, sensors, diagnostic recording/measurement, etc., can solve problems such as inability to form images

Inactive Publication Date: 2011-01-12
王任直 +3
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  • Abstract
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  • Application Information

AI Technical Summary

Problems solved by technology

However, after setting according to the usual parameters of the existing MRI machine, the scan of the cynomolgus monkey cannot form an effective and recognizable image

Method used

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  • Cynomolgus monkey magnetic resonance scanning method
  • Cynomolgus monkey magnetic resonance scanning method
  • Cynomolgus monkey magnetic resonance scanning method

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Embodiment Construction

[0010] Cynomolgus monkey, male, about 3.5 years old, weighing about 4.2kg, provided by the Experimental Animal Center of the Academy of Military Medical Sciences. Ordinary grade, license number: SCXK (military) 2002-001. Enter the animal room to quarantine for 2 weeks. The animal laboratory is a non-rodent facility of the Institute of Experimental Animals, Chinese Academy of Medical Sciences, with an ordinary-level environment, license number: SYXK (Beijing) 2005-0042, temperature 18-28°C, relative humidity: 40-70%, mechanical ventilation Wind, illuminance 150-300Lux, lighting time 12h / 12h. The cages were sterilized before they were put into use, and they were kept in single cages. Add food once a day in the morning and afternoon, and give fruit once a day. The first-class monkey feed, ordinary grade, was supplied by the Experimental Animal Center of the Academy of Military Medical Sciences of the Chinese People's Liberation Army, and the certificate number was SCXK-(Army) ...

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Abstract

The invention aims at improving cynomolgus magnetic resonance scanning methods and consequently providing legible brain magnetic resonance images. The invention provides a cynomolgus magnetic resonance scanning method that utilizes a Philips Intera A chiva 3.0T magnetic resonance machine for scanning, a T1 scanning sequence is IR with the visual field of 120mm, the TR / TE of 2153ms / 13ms, the seam thickness / interval of 3mm / 0.3mm and the matrix of 256 multiplied by 256, while a T2 weighted image scanning sequence is SE with the visual field of 12cm multiplied by 12cm, the TR / TE of 3200ms / 102ms, the seam thickness / interval of 3mm / 0.3mm and the matrix of 256 multiplied by 256. The cynomolgus magnetic resonance scanning method can provide legible brain magnetic resonance images, and has greatersignificance in the displaying of cynomolgus craniocerebral anatomical structure and cytological marking and magnetic resonance tracing after brain transplantation.

Description

technical field [0001] The invention relates to a magnetic resonance scanning method of cynomolgus monkeys. It should be noted that the present invention is not a method for diagnosing diseases, but a method for displaying the anatomical structure or experimental markers of the cranial brain of experimental animals. Background technique [0002] The main principle of MRI (magnetic resonance scanning) is to use the magnetic field generated by the magnetic resonance machine to make the radio wave receiver placed close to the body detect tiny signals from the inside of the body, and the computer converts these tiny signals to obtain images. The effective imaging time of MRI is long, the dynamic migration process of cells can be observed, the spatial and temporal resolution is high, and the contrast is good, so it has a promising prospect in in vivo tracing. In vivo tracer is one of the most effective means in modern medical research. MRI imaging can be used to directly observe...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B5/055
Inventor 冯铭张楠尹晓明冯晨璐朱华卢姗魏俊吉赵绪娜代小伟刘颖
Owner 王任直
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