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Skin photoaging prophylactic agent

A technology for skin photoaging and preventive agent, which can be used in skin care preparations, skin diseases, cosmetics, etc., and can solve problems such as difficulty in skin problems, rough skin and safety.

Inactive Publication Date: 2008-11-12
SINPHAR TIAN LI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, even with these cosmetic products, it can be difficult to completely control skin problems caused by sun exposure
In addition, as a method of improving the above-mentioned skin photoaging symptoms, it is well known that the use of all-trans retinoic acid applied externally is an effective method (refer to Gilchrest ed. Photodamage: Blackwell Science Company, 1995, etc.), but due to the presence of all-trans retinoic acid It can cause scientific problems in fragrance cosmetics such as skin roughness, and also has safety problems, so it can only be used according to the guidance of a doctor in Japan, so people are eagerly looking forward to developing an effective and safe preventive / Drugs for improving photoaging and skin external preparations

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0076] Although examples of the present invention have been described, the present invention is not limited to these examples.

[0077] Example

preparation Embodiment 1

[0078] Preparation Example 1 of Skin Photoaging Preventive Agent of the Present Invention: Preparation of Extract of Cistanche tubulosa (Cistanche tubulosa) (hereinafter referred to simply as "Cistanche tubulosa")

[0079] [Extraction process]

[0080] The thin slice 10kg of the fresh stem of Cistanche tubulosa is immersed in the water of 8 times of this thin slice. After immersing the flakes in water for 1 hour, they were decocted in water for 2 hours. The decocted mixture was filtered to obtain a first filtrate. Next, the residue of the decocted mixture was mixed with 40% ethanol in an amount 4 times that of the residue, decocted for 4 hours, and the decocted mixture was filtered to obtain a second filtrate. For the residue of the second filtrate, the same operation as above was repeated twice to obtain a third filtrate and a fourth filtrate. The above four filtrates were combined and concentrated in vacuo until the specific gravity of the concentrated solution was 1.05 (...

Embodiment 2

[0088] The pure product of echinacoside (manufactured by Xinghui Pharmaceutical Industry Co., Ltd.) was used in Example 2, and the pure product of acteoside (manufactured by Xinghui Pharmaceutical Industry Co., Ltd.) was used in Example 3.

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Abstract

The objective of the invention is to provide a photo-aging prophylactic agent for skin with novel ingredients and foods using the photo-aging prophylactic agent for skin, medicaments for mammals including human beings and a skin external agent, as well as feed for mammals. The inventive photo-aging prophylactic agent for skin is characterized by taking extracts of Orobanchaceae plants as effective ingredients. The photo-aging prophylactic agent for skin preferably comprises phenylethanoid glycosides compounds as effective ingredients. Moreover, the photo-aging prophylactic agent for skin preferably comprises at least one of echinacoside and acteoside as the phenylethanoid glycosides compounds. On top of that, the photo-aging prophylactic agent for skin preferably comprises both echinacoside and acteoside as the phenylethanoid glycosides compounds. In addition, the photo-aging prophylactic agent for skin can be employed as medicaments for mammals including human beings, skin external agents, consumptive foods and feed for mammals.

Description

technical field [0001] The present invention relates to a skin photoaging preventive agent using a novel ingredient. The present invention can be widely used in medicines for mammals including humans, external preparations for skin, foods, and the like. Background technique [0002] It has been known since ancient times that fresh stems of Cistanche herbs are effective for the treatment of infertility, impotence, constipation, etc. (refer to Patent Document 1). Moreover, preparations made from the fresh stems of these perennial herbs serve as nourishment for the blood and kidneys. These perennial parasitic herbs are widely cultivated in Northwest China, where they are called "desert ginseng". Among them, Cistanche tubulosa (Schrenk.) Wight, a wholly parasitic plant of the Cistanche family, is the one with the largest cultivation yield in the Cistanche family. [0003] Japanese scholars have systematically studied the chemical components and pharmacological activities of C...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7028A61K36/64A61K8/60A61K8/97A61P17/00A61Q19/08A23L1/30A23K10/30A23K20/00A23K20/111A23K20/163
Inventor 田中润司菊池光伦下田博司村井弘道
Owner SINPHAR TIAN LI PHARMA
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