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Shenshe composition and preparation thereof

A technology of composition and red ginseng, applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problems of insufficient utilization of medicinal material resources, cumbersome operation process, and failure to extract polysaccharide components of Hedyotis diffusa

Active Publication Date: 2011-05-25
XIAN XINTONG PHARM RES CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The patent has many medicinal flavors and cumbersome operation process. The extract is either saponin or polysaccharide, rather than saponin and polysaccharide. The two components are organically combined to play a synergistic effect.
On the other hand, the polysaccharide components of Hedyotis diffusa were not extracted
None of the disclosed pharmaceutical compositions fully utilizes medicinal material resources

Method used

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  • Shenshe composition and preparation thereof
  • Shenshe composition and preparation thereof
  • Shenshe composition and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Embodiment one: the preparation of Shentong tablet

[0042] 1.1 Preparation of red ginseng and Hedyotis diffusa extracts

[0043] 1) Take 1800g of red ginseng and grind it into the coarsest powder, 1200g of Hedyotis diffusa, cut it into sections, add 8 times of 75% ethanol, reflux for 1 hour each time, filter, dry the filter residue, and set aside;

[0044] 2) Combine the filtrates, adjust the pH to 8.38 with sodium hydroxide, let stand for 8-12 hours, filter, adjust the pH of the filtrate to 6.45 with dilute hydrochloric acid, place and filter, recover the ethanol from the filtrate until it has no alcohol smell, and dry the paste under reduced pressure or Spray drying to obtain 200 g of alcohol extract saponins, flavonoids, p-hydroxycoumaric acid, triterpenoids and other components.

[0045] 3) Take the dried medicinal residues and add water to decoct twice, add 8 times of water for the first time, decoct for 1 hour, add 6 times of water for the second time, decoct fo...

Embodiment 2

[0057] Embodiment two: the preparation of Shen Tongu oral liquid

[0058] 2.1 Preparation of red ginseng and Hedyotis diffusa extracts

[0059] 1) Take 1000g of red ginseng and pulverize into the coarsest powder, 800g of Hedyotis diffusa, cut into sections, add 6 times of 80% ethanol, reflux for 1 hour each time, filter, dry the filter residue, and set aside;

[0060] 2) Combine the filtrates, adjust the pH value to 8.67 with sodium hydroxide, let it stand for 8-12 hours, filter, adjust the pH value of the filtrate to 6.55 with dilute hydrochloric acid, place and filter, recover the ethanol from the filtrate until it has no alcohol smell, and obtain the saponin of the alcohol extract , flavonoids, p-hydroxycoumaric acid, triterpenoids and other ingredients.

[0061] 3) Take the dried medicinal residues and add water to decoct twice, add 10 times the water for the first time, decoct for 1 hour, add 8 times the water for the second time, decoct for 0.5 hours, filter, and combin...

Embodiment 3

[0064]Embodiment Three: Preparation of Shentong Injection

[0065] 3.1 Preparation of red ginseng and Hedyotis diffusa extracts

[0066] 1) Take 800g of red ginseng and pulverize into the coarsest powder, 1200g of Hedyotis diffusa, cut into sections, add 8 times of 80% ethanol, reflux for 1 hour each time, filter, dry the filter residue, and set aside;

[0067] 2) Combine the filtrates, adjust the pH value to 8.38 with sodium hydroxide, let stand for 8-12 hours, filter, adjust the pH value of the filtrate to 6.45 with dilute hydrochloric acid, place and filter, recover the ethanol from the filtrate until it has no alcohol smell, and obtain the saponin of the alcohol extract , flavonoids, p-hydroxycoumaric acid, triterpenoids and other ingredients.

[0068] 3) Take the dried medicinal residues and add water to decoct twice, add 8 times of water for the first time, decoct for 1 hour, add 8 times of water for the second time, decoct for 0.5 hours, filter, and combine the filtrat...

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Abstract

The invention relates to a shenshe combination and the preparation method of the shenshe combination. The composition of the shenshe combination comprises 80 to 150 portions of red ginseng and 60 to 120 portions of herba oldenlandiae or the alcohol extracts and water extracts prepared by the raw medicine materials of 80 to 150 portions of red ginseng and 60 to 120 portions of herba oldenlandiae. The shenshe combination provides the medicinal composition of the red ginseng and the herba oldenlandiae that can increase utilization rate to the utmost extend, save resources and has good clinical curative effect and stable quality. In addition, preparation which is easy for clinical use is obtained, and the shenshe combination and the preparation method there of have better curative effect on treating cancer and relieving the pain of patients.

Description

technical field [0001] The invention relates to a ginseng tongue composition and a preparation method thereof, in particular to a ginseng tongue composition and a preparation method thereof which are clinically used to suppress tumors, enhance immunity, prevent and treat various cancers. Background technique [0002] Cancer, also called malignant tumor, is a disease with high morbidity and mortality after cardiovascular and cerebrovascular diseases, which seriously threatens human health. It is learned from the Department of Diseases of the Ministry of Health that in the 1970s, malignant tumors in my country only accounted for the third cause of death, and since the 1990s, it has risen to the second place. Compared with 30 years ago, the incidence of malignant tumors in my country has increased by 29.4%, and the growth rate is still 11.6% after eliminating the influence of different age groups. Experts predict that in the next 20-30 years, the incidence and mortality of tum...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P37/04A61P35/00A61K36/74
Inventor 王红
Owner XIAN XINTONG PHARM RES CO LTD
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