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Application of cerebral tissue fluid and nerve growth factor in preparing combination medicine for treating infantile cerebral paralysis

A nerve growth factor, a technology for children with cerebral palsy, which can be used in drug combinations, nervous system diseases, pharmaceutical formulations, etc., can solve the problems of not being able to use all drugs, and the causes of children's cerebral palsy are unknown, and achieve obvious treatment and rehabilitation effects, restore intelligence, improve effect of life

Inactive Publication Date: 2008-04-30
王文生
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In view of the immature development of children at this stage and the unknown cause of cerebral palsy in children, the applicant believes that it is impossible to fully play the role of drugs and achieve the best therapeutic purpose by relying solely on the treatment concept of western medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Embodiment 1 Preparation of brain tissue fluid and nerve production factor combined drug

[0017] Cerebral tissue fluid injection was purchased from Harbin Pharmaceutical No. 3 Factory, China, with a specification of 2ml×10 tubes×60 boxes. Nerve production factor for injection was purchased from Lanzhou Institute of Biological Products, with a specification of 18 μg (9000 units) per branch. Prepare 2ml of nerve production factor injection, wherein the nerve production factor is 2000 units, mix with 2ml of brain tissue fluid injection (equivalent to 0.8g of fresh brain), and use immediately.

Embodiment 2

[0018] Embodiment 2 drug efficacy experiment

[0019] Clinical judgment criteria for children with cerebral palsy:

[0020] (1) Delay in motor development: unable to raise head for 100 days; thumbs retracted after 4 months, unable to open hands after 5 months, unable to reach out to grasp objects; 4-6 months unable to smile, unrecognizable, abnormal appearance; Can't sit at 8 months; can't crawl at 10 months; can't walk at 15 months.

[0021] (2) Reduced active activity.

[0022] (3) Abnormal reflex: the original reflex disappears with delay; the protective reflex is weakened or does not appear. For example, when sitting, push the child in all directions, and the child will not support it with his hands.

[0023] (4) Abnormal muscle tone and abnormal posture. In the upright position, the lower limbs are internally rotated and straightened, the feet are drooping, and the legs are crossed in a scissors shape; from supine to sitting up, the head is tilted back, the lower limb...

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Abstract

The invention provides the application of brain tissue fluid and nerve growth factor which are used to prepare drug combinations for treating children's cerebral pasly. The invention provides the drug combinations of the brain fluid and the nerve growth factor. The route of medication of the drug combinations is that the drug is injected through channels and then through outer odd acupuncture point. The drug combination has the advantages of being capable of adjusting brain cells of children patients to regenerate, activate and restore injured and oxygen-poor brain cells, also being capable of effectively restoring functional disturbances of intelligence, language, motion and behavior, having distinguished therapeutic and curative effects. The drug provides a very unique and effective choice for the treatment and rehabilitation treatment work of the children's cerebral pasly, ensuring the children patients who are infected with cerebral pasly to improve the quality of life and survivorship, thereby reducing mental and economic burdens of society and families.

Description

technical field [0001] The invention relates to the fields of traditional Chinese medicine and western medicine, in particular to the application of brain tissue fluid and nerve growth factor in the preparation of combined medicine for treating children with cerebral palsy. Background technique [0002] Cerebral palsy in children starts from the mother's conception and is caused by genetic factors, family factors, medication factors, environmental factors and other reasons. Motherland medicine believes that it is caused by factors such as congenital deficiency or loss of kidney qi, brain orifice and marrow dystrophy. The disease causes great economic burden and mental pressure to society and family. [0003] At present, the drugs for the treatment of children with cerebral palsy are mostly administered alone, but the therapeutic effects vary greatly. The applicant thinks that this is related to the complication of the cause of cerebral palsy in children, and the cause is u...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/18A61P25/00A61K35/30
Inventor 王文生
Owner 王文生
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