Compounds with antimicrobial antiviral activity
A compound and adduct technology, applied in the field of medicine, can solve the problems of inconvenient clinical application and increased bacterial resistance, and achieve the effect of enriching the variety of clinical drugs
Active Publication Date: 2010-12-15
吉林津升制药有限公司
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Problems solved by technology
The emergence and application of antibiotics have played a huge role in the prevention and treatment of infectious diseases, but at the same time, the overuse of antibiotics has led to the continuous increase of bacterial resistance, as well as the limitation of absorption in the digestive tract, which has brought a lot of inconvenience to clinical application
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The present invention belongs to the field of medical technology and relates to a compound and adduct thereof with antibacterial and antiviral activity; wherein, R, n, and m are defined as in the specification. The present invention also relates to drug compositions containing the compound and adduct, and the application of the compound and adduct in preparation of drugs for treating and / or preventing infectious diseases. The compound and adduct of the present invention have broad-spectrum and high-efficiency antibacterial and antiviral activity; in vitro and in vivo, the compound and adduct have high antibacterial activity for Gram-positive and negative bacteria, aerobic and anaerobic bacteria and fungi. At the same time, the compound and adduct have high anti-virus activity and good values for clinical application.
Description
1. Technical field The present invention relates to compounds with antibacterial and antiviral activity and their adducts, pharmaceutical compositions containing these compounds or their adducts, and the use of these compounds or their adducts in the preparation of medicines for treating and / or preventing infectious diseases The application belongs to the field of medical technology. 2. Background technology Infectious diseases are diseases caused by bacteria, viruses, fungi, etc. It is one of the major clinical diseases and seriously endangers human life and health. The emergence and application of antibiotics have played a huge role in the prevention and treatment of infectious diseases, but at the same time, the overuse of antibiotics has led to the continuous increase of bacterial resistance, as well as the limitation of absorption in the digestive tract, which has brought a lot of inconvenience to clinical application. Due to the large number of patients with infectio...
Claims
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IPC IPC(8): C07D285/08C07D277/40C07D277/56C07D233/92C07D249/10A61K31/433A61K31/426A61K31/4164A61K31/4196A61P31/00
Inventor 黄振华
Owner 吉林津升制药有限公司
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