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Two-channel self calibrating multiple parameters rapid whole blood biochemistry analyzing sensor

A sensor, self-calibration technology, applied in the field of biosensors, can solve complex problems

Inactive Publication Date: 2007-12-05
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the current literature and patent reports, the fluid control of the calibration solution and the measured blood is more complicated, requiring control elements such as pumps and valves, such as the i-STAT handheld blood gas / pH+electrolyte analyzer produced by i-STAT

Method used

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  • Two-channel self calibrating multiple parameters rapid whole blood biochemistry analyzing sensor

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Embodiment Construction

[0014] As shown in Figure 1, a dual-channel self-calibration multi-parameter fast whole blood biochemical analysis sensor includes an upper hydrophilic coating 2, a lower sensor substrate 1, an upper hydrophilic coating 2 and a lower sensor substrate The calibration liquid package 4 between 1, the lower sensor substrate 1 is provided with a calibration liquid channel and a test liquid channel, and the calibration liquid channel is composed of a calibration liquid injection area 4, a microfluidic channel 5, and a calibration liquid waste recovery pool 12. The test liquid channel is composed of a test liquid injection area 8 , a microfluidic channel 9 , and a waste liquid recovery pool 11 for the test liquid.

[0015] There are several pairs of blood chemistry, blood electrolyte and blood gas measurement electrodes symmetrically arranged in the two microfluidic channels 5 and 9, respectively forming the calibration electrode array 7 and the measurement electrode array 6, and the ...

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Abstract

The invention discloses a rapid full-blood biochemical analyzing sensor of double-channel self-gauge multi-parameter, which comprises the following parts: upper hydrophilic tectorial, lower sensor base and calibration fluid, wherein the calibration fluid channel and testing liquid channel are set on the lower sensor base with each channel composed of injecting area, micro-flow channel and recycling pond; several couples of measuring electrode of blood chemistry, blood electrolyte and blood measurement are set in two micro-flow channels symmetrically, which form the electrode array and the measuring electrode array; two working electrodes of each electrode solidifies the biochemical agent with the same species to participate the measuring reaction; different enzyme or electrolyte and blood gas sensitive material are fixed between each couple of electrode. The invention makes one-batch making and compact adjacent electrode possess high-degree consistency and simple double-channel structure to solve the on-site marking problem in the rapid full-blood analysis, which improves the measuring speed greatly and reduces the testing cost without adding electromechanical structure.

Description

technical field [0001] The invention relates to a biological sensor, in particular to a double-channel self-calibration multi-parameter fast whole blood biochemical analysis sensor. Background technique [0002] Clinical biochemical testing is an indispensable means of blood component analysis. Traditional clinical biochemical tests are carried out on large-scale biochemical analyzers in hospitals, which require non-polluting transfer of test samples and are performed by professional operators, which is time-consuming and expensive, and cannot adapt to the trend of family medicine, nor can it meet the needs of surgery, emergency, field rescue, etc. Time is life" occasion needs. Point of Care Testing (POCT) allows doctors to make the most efficient clinical judgments in the shortest possible time, bringing revolutionary progress to medical care. At present, the bedside test items mainly focus on the analysis of blood biochemistry, blood electrolytes, blood gas and blood coa...

Claims

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Application Information

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IPC IPC(8): G01N27/416G01N27/00G01N33/48
Inventor 李光王酉胡萌
Owner ZHEJIANG UNIV
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