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Novel formulation of shenqiwendan decoction and production method thereof

A technology of Shenqi Wendan and new dosage forms, which is applied to the new dosage forms of Shenqi Wendan Decoction and its production field, which can solve the problems of inability to commercialize production, inconvenient carrying, and inability to store for a long time, so as to improve bioavailability and reduce Adverse reactions, effects of portability

Active Publication Date: 2010-04-07
黄达驹 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] Shenqi Wendan Decoction is a new dosage form of oral traditional Chinese medicine preparation, which has accurate dosage and stable quality, and is suitable for large-scale commercial production. Disadvantages of chemical production

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Example 1 (Shenqi Wendan Decoction Oral Liquid):

[0067] Take the prescription amount of 12 kg of Pinellia, 12 kg of ginger, 40 kg of Codonopsis, 40 kg of Astragalus, 12 kg of Zhuru, 12 kg of Citrus aurantium, 18 kg of tangerine peel, 6 kg of licorice, 10 kg of Poria and 6 kg of jujube. Soak the medicinal materials in water for 0.5 hours; add water for decocting 2 times; the first time 2.5h, the second time 1h; combine the decoction, filter, concentrate the filtrate under reduced pressure, add 95% ethanol to make the alcohol content reach 65%, statically Leave it for 48 hours, recover ethanol, add distilled water to a total of 20L, stir well, filter, adjust the pH to 6.5, potting, and sterilizing, and it is ready.

Embodiment 2

[0068] Example 2 (Shenqi Wendan Decoction Oral Liquid):

[0069] The medicinal materials were decocted twice, the first decocted for 1 hour, the second decocted for 45 minutes, combined the medicinal solution, filtered, and the filtrate was concentrated to a relative density of 1.17 (80℃), cooled, and 95% ethanol was added to make the alcohol content 65% Let it stand for 48h to precipitate and filter. The filtrate recovers ethanol and concentrates to a relative density of 1.20 (80°C). Add water to adjust to 1000L, add cyclamate 3kg, sodium benzoate 3kg, stir, cool, filter, potting, and sterilize.

Embodiment 3

[0070] Example 3 (Shenqi Wendan Decoction Oral Liquid):

[0071] The medicinal materials were immersed in water for 1 hour, and decocted twice according to the decoction method, the first time was 2 hours, and the second time was 1.5 hours. Combine the two decoctions, filter, and let the filtrate stand for 24h; take the supernatant and concentrate to 500L, add ethanol to make the alcohol content reach 60%; stand for precipitation, filter, and recover ethanol; adjust the total amount of the filtrate to 1000L , Add 2kg of sodium benzoate and 1kg of sodium cyclamate, mix well, can seal, sterilize, and get ready.

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PUM

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Abstract

The invention relates to a Chinese medicinal preparation and process for preparation, wherein the main raw materials include pinellia tuber, fresh ginger, pilose asiabell root, astragalus root, bambooshavings, immature bitter orange, dried orange peel, licorice root, poria cocos wolf and jujube, and can be used for treating coronary disease and auricular fibrillation.

Description

Technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations and production methods thereof. [0002] The new dosage form of Shenqi Wendan Decoction is based on the traditional formula of Shenqi Wendan Decoction, applying modern Chinese medicine theory and new technology, new technology and new equipment for the production of Chinese medicine preparations. A new dosage form of traditional Chinese medicine oral preparation that reflects the characteristics of traditional Chinese medicine and can effectively control product quality. Specifically, it uses ten Chinese medicinal materials such as Pinellia, ginger, Codonopsis, Astragalus, Zhuru, Citrus aurantium, tangerine peel, licorice, Poria and Jujube as the main raw materials, and has developed a kind of medicine that can nourish qi, invigorate the spleen and reduce dampness. Phlegm-removing effect, mainly used for the new formulation of Chinese medicine oral preparation of Shenq...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61K36/899A61K36/8888A61K36/752A61K36/75A61K36/725A61K36/481A61K36/484A61K36/344A61K36/076A61K9/48A61K9/20A61K9/16A61K9/08A61P9/10A61P9/00
Inventor 史冠君黄达驹张展飞何鹤锋
Owner 黄达驹
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