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A medicine for treating vaginal bleeding caused by drug induced abortion and method for preparing the same

A technology for treating drug and vaginal bleeding, which is applied in the field of medicine and can solve the problems of affecting the curative effect of drugs, unsatisfactory effect, and inconvenience in taking, so as to shorten the time of vaginal bleeding, increase the rate of complete abortion, and reduce the amount of bleeding

Active Publication Date: 2006-12-13
SICHUAN LVYE BAO GUANG PHARMA IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these traditional prescriptions need to be temporarily formulated according to the specific conditions of the patients, and they are temporarily boiled, which is inconvenient to take, and may affect the efficacy of the medicine due to improper operation during boiling.
At present, although there are some Chinese patent medicines taken orally after childbirth in clinical practice, such as Chanfukang, Gongxuening, etc., they are mainly aimed at patients after normal childbirth, and the effect is not ideal when used to treat vaginal bleeding after medical abortion

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] The present embodiment medicine is made by the raw material drug of following weight ratio:

[0017] 3 parts of Astragalus, 6 parts of Motherwort, 2 parts of Chuanxiong, and 3 parts of Puhuang.

[0018] The medicine of this example can be prepared into granules by the following method: take the raw materials of the ratio, add 8 times the amount of 50% ethanol, reflux extraction 3 times, each time for 1 hour, filter, combine the filtrate, and concentrate 1ml of medicinal solution is equivalent to 1g of raw medicinal material, add 2 times of water, let it stand for 16 hours, filter, take the filtrate and concentrate to a relative density of about 1.10-1.15 (60°C), add appropriate amount of sucrose and starch, follow the routine of granules The preparation method comprises the steps of granulating and subpackaging into granules of certain specifications.

Embodiment 2

[0020] The present embodiment medicine is made by the raw material drug of following weight ratio:

[0021] 1 part of Astragalus, 6 parts of Motherwort, 5 parts of Chuanxiong, and 3 parts of Puhuang.

[0022] The medicine of this example can be prepared into granules by the following method: take the raw materials of the ratio, add 10 times the amount of 95% ethanol, reflux extraction twice, each time for 1 hour, filter, combine the filtrates, and concentrate 1ml of medicinal liquid is equivalent to 1.5g of the original medicinal material, add 3 times of water, let it stand for 12 hours, filter, take the filtrate and concentrate to a relative density of about 1.05-1.10 (60°C), add appropriate amount of sucrose, corn starch, mannitol, According to the conventional preparation method of granules, after granulation, it can be divided into granules of certain specifications.

Embodiment 3

[0024] The present embodiment medicine is made by the raw material drug of following weight ratio:

[0025] 5 parts of Astragalus, 2 parts of Motherwort, 1 part of Chuanxiong, and 5 parts of Puhuang.

[0026] The medicine in this example can be prepared into granules by the following method: take the raw materials of the above ratio, add 6 times the amount of 30% ethanol, reflux extraction 4 times, each time for 2 hours, filter, combine the filtrates, and concentrate 1ml of liquid medicine is equivalent to about 0.5g of the original medicinal material, add 1 time of water, let it stand for 24 hours, filter, take the filtrate and concentrate to a relative density of about 1.15-1.20 (60°C), add appropriate amount of starch, microcrystalline cellulose, hard Magnesium fatty acid, according to the conventional preparation method of photographic preparation, tablet after granulation, make the tablet of certain specification and get final product.

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Abstract

The invention relates to a pharmaceutical composition for treating post abortion colporrhagia and process for preparation, wherein the raw material medicaments include (by weight proportion) astragalus root 0.5-5 parts, motherwort 1-20 parts, rhizome of Sichuan lovage 0.5-15 parts and cattail pollen 0.5-15 parts.

Description

technical field [0001] The invention relates to a medicine for treating vaginal bleeding after drug abortion and a preparation method thereof, which belong to medicine [0002] technology field. Background technique [0003] Prolonged vaginal bleeding after medical abortion is a major clinical problem that has not yet been resolved. In recent years, in order to alleviate the pain of artificial abortion, more and more unwanted pregnancies choose to use medical abortion, that is, the combination of mifepristone and misoprostol is used to terminate early pregnancy, and the success rate of abortion can be as high as 90-95% . However, in the case of medical abortion, even in patients with complete abortion, although the chorionic fetal sac has been discharged, the decidua tissue in the uterus is slowly discharged, so the vaginal bleeding time is generally longer, with an average of 17-25 days. Up to 40 days. In some patients, due to the attachment of degenerated villi to the ...

Claims

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Application Information

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IPC IPC(8): A61K36/88A61P7/04A61P15/00
Inventor 郭勃徐华模张德翠
Owner SICHUAN LVYE BAO GUANG PHARMA IND
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