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Microscopically-observable cone-plate shear field generator

A technology of generating device and shear field, which is applied in biological testing, material inspection products, etc., can solve the problems of inability to disassemble and clean, inconvenient disassembly and cleaning of cone and plate, unfavorable scientific experiments, etc., and achieves convenient cleaning and adherent cell culture, It is convenient for real-time observation and high-precision adjustment effect

Inactive Publication Date: 2006-11-22
BEIHANG UNIV
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But this device has certain disadvantages: firstly, the core part of the device, the cone-plate shearing device, uses the cone and the plate itself as the axis of rotation, and cannot be easily disassembled and cleaned by the gears around the cone. Installation is difficult to achieve the original accuracy
Adding pipes in this environment has an irreversible effect on the shear field - there is no longer a uniform shear field between the cone and plate, which is not conducive to rigorous scientific experiments
Third, due to the inconvenient disassembly and cleaning of the cone and plate, the device cannot be used to cultivate adherent cells, so it is impossible to observe the behavior of adherent cells in the shear field

Method used

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  • Microscopically-observable cone-plate shear field generator
  • Microscopically-observable cone-plate shear field generator
  • Microscopically-observable cone-plate shear field generator

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Embodiment Construction

[0020] Such as figure 1 Shown, be a kind of microscopically observable cone-plate shear field generation device provided by the present invention, it comprises:

[0021] a base 1;

[0022] A longitudinal driving device 2, which is arranged on the base 1;

[0023] A U-shaped bracket 3, the bottom of which is connected to the longitudinal driving device 2;

[0024] A liquid container bracket 4, which is arranged on one side of the U-shaped support 3, and a liquid container 41 is arranged on the liquid container bracket 4;

[0025] A vertical driving device 5, which is arranged on the other side of the U-shaped support 3;

[0026] A cone plate support 6, its rear end is connected and arranged on the vertical drive device 5, the front end lower part of the cone plate support 6 is provided with a cone plate 61, the cone plate 61 is facing the liquid container 41, and is the same as the liquid container 41. axis;

[0027] A motor 7 is arranged on the cone-plate support 6 , and ...

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Abstract

The disclosed generator for cone plate shearing field comprises: a base with a vertical drive device, a U-shape frame with bottom connected to the drive device, a frame for fill-liquid utensil on one side of U-shape frame with another side fixed another vertical drive device, a cone plate frame with back end connected to last drive device and its front end fixed a cone plate opposite the utensil, and a motor with gear on cone plate frame. This invention is fit to different microscope and brings convenience to user.

Description

technical field [0001] The invention relates to a cone-plate shear field generating device, in particular to a microscopically observable cone-plate shear field generating device for basic research on the behavior of adherent cultured cells and suspension cells in a flow field. Background technique [0002] When the body fluid of the human body flows in the lumen, it will cause a shear field (such as blood flowing in the blood vessel). The cells in the human lumen, including suspension cells (such as blood cells) and cells growing on the wall (such as endothelial cells), in The metabolism and growth status in the shear field correspond to certain physiological and pathological characteristics. For example, red blood cells are deformed by the shear field in the process of entering the capillary, so that they can pass through the capillary smoothly; platelets can aggregate under the induction of high shear field, causing arterial thrombosis and endangering human health; The i...

Claims

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Application Information

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IPC IPC(8): G01N33/48
Inventor 杨春孙琦黄有奇程绪平庄逢源
Owner BEIHANG UNIV
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