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Chinese medicine composition for treating phthisis and use thereof

A composition and technology for pulmonary tuberculosis, which are applied in the directions of drug delivery, medical preparations containing active ingredients, and pharmaceutical formulations, and can solve problems such as toxic side effects, decreased sensitivity of Mycobacterium tuberculosis, and threats to health.

Inactive Publication Date: 2006-08-09
SHENYANG HONGQI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As a result, the effect of the original anti-tuberculosis drugs is obviously not as good as before, and some anti-tuberculosis drugs with better efficacy, such as rifampicin, isoniazid, streptomycin, etc., are significantly less sensitive to Mycoba

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The preparation method of syrup of the present invention:

[0021] Weigh each raw material: 450 grams of garlic, 450 grams of Prunella vulgaris, 400 grams of Polygonum multiflorum, 400 grams of Baibu, 250 grams of Bletilla striata, 250 grams of Rhizoma Polygonatum, decoct in water twice, each time for 1 hour, filter, combine the filtrates, and condense into a thick paste , add ethanol for precipitation twice, so that the alcohol content reaches 65% for the first time, and 80% for the second time, filter, recover ethanol and concentrate to about 700mL, add sucrose and ethylparaben alcohol solution while hot and stir to dissolve , add boiling water to the full amount, stir well and serve.

Embodiment 2

[0023] The preparation method of granule electuary of the present invention:

[0024] Weigh 500 grams of garlic, 500 grams of Prunella vulgaris, 500 grams of Polygonum multiflorum, 300 grams of Baibu, 300 grams of Bletilla striata, and 300 grams of Polygonatum. Grind the above-mentioned medicine into coarse powder, decoct in water for two times, the first time for 2 hours, the second time for 1 hour, filter, the filtrate is concentrated into a thick paste, dried, crushed through a 100-mesh sieve, mixed, moistened, softened, and formed Take out the agglomerates and make granule granules.

Embodiment 3

[0026] Weigh the garlic, Prunella vulgaris, and Polygonum multiflorum with 70% to 95% ethanol for reflux extraction twice, combine the two extracts, recover the ethanol, and dry at 45 to 55°C to obtain dry extract 1; The residues of Polygonatum, Bletilla striata, Bletilla striata, Garlic, Prunella vulgaris, and Polygonum multiflorum alcohol extraction in the weight ratio are decocted twice, each time adding water to cover the surface of the medicine, combining the decoction twice, and filtering to obtain the filtrate 2. Concentrate the filtrate into an extract with a specific gravity of 1.15 to 1.35, and dry it at 45 to 55°C to obtain dry extract 2; combine dry extracts 1 and 2, and pulverize them into powder to prepare the active ingredient of the drug of the present invention; The obtained active ingredient is thoroughly mixed with pharmaceutically acceptable additives such as flavoring agents and auxiliary materials to prepare any pharmaceutical dosage form. If the above-me...

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Abstract

The invention discloses a Chinese medicinal combination for curing pulmonary tuberculosis and the application thereof, composed of garlic, Common Selfheal Fruit-Spike, Tuber Fleeceflower Root, Tuber Stemona Root, Bletilla tuber, King Solomonseal Rhizome, etc. And the preparing method includes the following steps of: weighing all raw materials in proportion, crushing and grinding them into powders, making water decoction or alcoholic extraction twice, 1-2 hours for the first time and 1-1.5 hour for the second time, filtering, concentrating the filtrate into ointment, and able to add in cane sugar and other additives to make syrup or drying secondary ointments made by alcoholic and water extractions, combing the dry ointments, crushing and passing through 100-mesh sieve, mixing uniformly, wetting, softening, forming into a mass and then taking out the mass, and making the mass into granular infusion or other preparations. And it is to be orally taken, convenient to use, tasting good, easy to be accepted by patients, having strong effect of prohibiting and eliminating tubercle bacilli, and having characters of Yin conversion rate up to above 55% within 9 months, total effective rate up to 98.47%, and less curing expenses, able to save the expenses by above 60% as compared with routine cure.

Description

technical field [0001] The invention relates to a Chinese patent medicine, in particular to a traditional Chinese medicine composition and application for treating pulmonary tuberculosis with Chinese medicine as the main component. Background technique [0002] Tuberculosis is a common and difficult disease, which is a relatively common chronic infectious disease caused by Mycobacterium tuberculosis infection. Tuberculosis can occur in various tissues and organs of the human body, but the lung is the most common, and tuberculosis that occurs in the lung is called pulmonary tuberculosis. The general clinical use of Western medicine and chemotherapy for the treatment of tuberculosis at home and abroad. The western medicine for modern clinical treatment of pulmonary tuberculosis mainly includes isoniazid: its main toxic and side effects are excitability, insomnia, peripheral nerve inflammation, and occasionally liver function damage; rifampicin: its main toxic and side effects...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K9/00A61K9/16A61K9/20A61K9/46A61K9/48A61P31/06
Inventor 杨雄志
Owner SHENYANG HONGQI PHARMA
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