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System for diagnosing schizophrenia and application thereof

A schizophrenia, neurotechnology, applied in the field of biomedicine, can solve the problem of lack of diagnostic markers for schizophrenia

Pending Publication Date: 2022-03-29
苏州市广济医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, we still lack diagnostic markers for schizophrenia due to heterogeneity in etiology and clinical variation

Method used

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  • System for diagnosing schizophrenia and application thereof
  • System for diagnosing schizophrenia and application thereof
  • System for diagnosing schizophrenia and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084] Embodiment 1. Screening and verification of influencing factors

[0085] 1. Subjects

[0086] A total of 69 patients with schizophrenia and 50 healthy controls participated in the study. Diagnoses were confirmed using the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) Structured Clinical Interview (SCID) tool. All subjects were right-handed, and the hearing evaluation (pure tone audiometry, 1000 Hz) was normal. The inclusion criteria for the registry of patients with schizophrenia were as follows:

[0087] 1) All clinically stable subjects have no history of neurological diseases or head trauma,

[0088] 2) No history of electric shock therapy in the past six months,

[0089] 3) No history of alcohol / drug dependence or abuse (except tobacco).

[0090] Patients were excluded due to unstable condition or IQ below 70.

[0091] During the study period, all patients received antipsychotic medication as usual. The healthy control gro...

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Abstract

The invention belongs to the field of biomedicine, and particularly relates to a schizophrenia diagnosis system and application thereof. In particular, the system includes a computing device that diagnoses schizophrenia based on neurocognitive features and / or electrophysiological features. The neurocognitive features are measured through an RBANS or Stroop test method, and the electrophysiological features are obtained through analysis after electroencephalogram detection.

Description

technical field [0001] The invention belongs to the field of biomedicine, and in particular relates to a system for diagnosing schizophrenia and its application. Background technique [0002] Schizophrenia is one of the most serious mental illnesses, affecting 20 million people worldwide. Schizophrenia usually has a slow or subacute onset in young adults. Clinically, it is often manifested as a syndrome with different symptoms, involving obstacles in perception, thinking, emotion, and behavior, as well as incoordination of mental activities. Patients generally have clear consciousness and basically normal intelligence, but some patients may experience cognitive impairment during the course of the disease. Studies have shown that cognitive deficits are one of the core features of the significant neurological deficits associated with schizophrenia and are often associated with poor prognosis. In addition, prepulse inhibition (PPI), which is considered an indicator of informa...

Claims

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Application Information

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IPC IPC(8): A61B5/00A61B5/16A61B5/377A61B5/38A61B5/389
CPCA61B5/4076A61B5/377A61B5/38A61B5/72A61B5/165A61B5/389
Inventor 殷光中贾秋放田晴张广亚王传跃
Owner 苏州市广济医院
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