Leave-on oral care compositions
An oral care and composition technology, applied in the field of oral care compositions, can solve the problems of insufficient viscosity/stickiness, difficult to spread, difficult to maintain, etc., and achieve the effects of improving hydration, accelerating repair, and reducing dry mouth
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Embodiment A
[0115] Example A: Examples 1 to 5
[0116] Examples 1 to 5 are the gel compositions according to the present invention shown in Table 1 below, wherein the amounts of the components are in % by weight. They can be suitably prepared by conventional methods selected by the formulator.
[0117] Table 1: Gel Composition Example 1 to Example 5
[0118]
[0119] *Sodium hyaluronate with a weight average molecular weight of about 1,400,000 Da.
Embodiment B
[0120] Example B: Viscosity and Mucoadhesion Data
[0121] The viscosity profile of Example 1 according to the invention and several benchmark products available on the market (Examples 6 to 9) were tested according to the rheological test described above. The results for the consistency coefficient K and velocity index n are listed in Table 2 below.
[0122] The mucoadhesion of the inventive examples and reference products (Examples 6 to 8) was tested by using the mucoadhesion test described above. The results are also summarized in Table 2 below.
[0123] Table 2: Viscosity and mucoadhesion of embodiment 1 of the present invention and reference product
[0124]
[0125] i) Sunstar G·U·M interdental gel (20160426) 13ml
[0126] ii) Gengigel Gingival Gel (1811121) 20ml
[0127] iii) Lion DENT HEALTH R Perio Care Gel Cream (62431) 10g
[0128] iv) Lion DENT.EX Syatema Interdental Gel (150214NC) 20ml
[0129] Table 2 shows the viscosity and mucoadhesion values of ...
Embodiment C
[0131] Example C: Consumer Sensory Test
[0132] Consumer sensory testing was conducted to measure consumer preference for Example 1 of the present invention relative to the benchmark products (Examples 6 to 9).
[0133] Qualified consumer groups are instructed to use series test products with no knowledge of product identity ie brand, ingredients, etc. A questionnaire was designed to obtain consumer ratings on direct questions (DQs), including (1) whether the product spread / spreads easily on the gums; (2) did the product show consistency in thickness / stickiness; and (3) did the product spread over the gums? Whether to stay on it for enough time. The grades given by consumers are divided into three levels, where "+++" means that more than 60% of consumers are preferred, "++" means that more than 40% but less than 60% of consumers are preferred, and "+" means less than 40% of consumers is preferred. For each aspect, Inventive Example 1 was scored as "+++", surpassing Compa...
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