Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Fermentation product of lotus leaf-hawthorn extract and application of active ingredients of fermentation product to inhibition of fat formation

An active ingredient and fat-inhibiting technology, which is applied in the direction of organic active ingredients, medical preparations containing active ingredients, plant/algae/fungus/moss ingredients, etc., can solve problems such as difficulties in implementation, physical damage caused by exercise methods, and limited effects

Active Publication Date: 2021-06-04
百岳特生物技术(上海)有限公司
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, diet control strictly requires a balanced diet and calorie intake, which is difficult to implement; and inappropriate exercise methods may cause physical damage
In addition, since the aforementioned two methods do not directly target adipocytes, their effect on fat reduction (especially the adipose tissue around the viscera) is limited.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Fermentation product of lotus leaf-hawthorn extract and application of active ingredients of fermentation product to inhibition of fat formation
  • Fermentation product of lotus leaf-hawthorn extract and application of active ingredients of fermentation product to inhibition of fat formation
  • Fermentation product of lotus leaf-hawthorn extract and application of active ingredients of fermentation product to inhibition of fat formation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0125] Example 1: The effect of the fermented product of lotus leaf hawthorn extract on reducing the fat content of adipocytes

[0126] Take the adipocytes provided in [Preparation Example C], divide them into three groups and culture them with the following medium respectively, at 37°C for 7 days, during which the medium is replaced every 3 days:

[0127] 1. Group I: adipocyte differentiation medium (500 microliters in total).

[0128] 2. Group II: adipocyte differentiation medium containing 5% (weight / weight) of the lotus leaf Hawthorn extract provided in [Preparation Example A-1] (500 microliters in total); and

[0129] 3. Group III: adipocyte differentiation medium containing 5% (weight / weight) of the fermented product of the lotus leaf hawthorn extract provided in [Preparation Example A-3] (500 microliters in total);

[0130] Afterwards, the cells provided by groups I to III were treated with staining and quantification steps as follows: medium was removed and cells were...

Embodiment 2

[0133] Example 2: The effect of different partitioning of the fermented product of lotus leaf hawthorn extract on reducing the fat content of adipocytes

[0134] Take the adipocytes provided in [Preparation Example C], divide them into four groups and culture them with the following medium respectively, at 37°C for 7 days, during which the medium is replaced every 3 days:

[0135] 1. Group i: adipocyte differentiation medium (500 microliters in total);

[0136] 2. Group ii: adipocyte differentiation medium containing 5% (weight / weight) of the fermented product of the lotus-leaf Hawthorn extract provided in [Preparation Example A-3] (500 microliters in total);

[0137] 3. Group iii: adipocyte differentiation medium containing 5% (weight / weight) of the n-butanol layer extract provided in [Preparation Example B-1] (500 microliters in total);

[0138] 4. Group iv: adipocyte differentiation medium containing 5% (weight / weight) of the aqueous layer extract provided in [Preparation ...

Embodiment 3

[0141] Embodiment 3: the effect of formula (I) to formula (III) compound in reducing the fat content of adipocytes

[0142] Take the adipocytes provided in [Preparation Example C], divide them into four groups and culture them with the following medium respectively, at 37°C for 7 days, during which the medium is replaced every 3 days:

[0143] 1. Group A: adipocyte differentiation medium (500 microliters in total);

[0144] 2. Group B: adipocyte differentiation medium containing 20 micrograms / ml [Preparation Example B-3] of the compound of formula (I) provided (500 microliters in total);

[0145] 3. Group C: the adipocyte differentiation medium (500 microliters in total) containing the compound of formula (II) provided by 20 micrograms / ml [Preparation Example B-3];

[0146] 4. Group D: adipocyte differentiation medium containing 20 μg / ml of the compound of formula (III) provided in [Preparation Example B-3] (500 μl in total).

[0147] Afterwards, the cells provided in Groups...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

Use of at least one of the following compounds of formula (I) to formula (III) is provided. Provided is a composition comprising a fermentation product of lotus leaf-hawthorn extract that can provide at least one of the above compounds of formula (I) to formula (III), and also provided is a method for preparing the fermentation product of lotus leaf-hawthorn extract.

Description

technical field [0001] The present invention relates to the application of at least one of the compounds of the following formula (I) to formula (III), especially related to the application of the above compounds in promoting the fat degradation ability of adipocytes, inhibiting the adipogenesis ability of adipocytes, making it difficult for individuals to form body fat, and / or apps that promote weight loss: [0002] [0003] The present invention further relates to a composition comprising a fermented product of a hawthorn extract capable of providing at least one of the above-mentioned compounds of formula (I) to formula (III), and a method for preparing the fermented product of a hawthorn extract. Background technique [0004] Obesity is a state of excess body fat. Internationally, body mass index (BMI) or waist circumference are usually used as indicators for evaluating obesity. In Taiwan, China, a BMI value greater than or equal to 24 and less than 27 indicates ove...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4745A61K36/734A61P3/04
CPCA61K31/4745A61K36/62A61K36/734A61P3/04A61K2236/19A61K2300/00A61K31/473A61K2236/331
Inventor 林咏翔庄伟秀
Owner 百岳特生物技术(上海)有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com