In-vitro cardiopulmonary combined perfusion system and perfusion method

Abstract

The invention aims to provide an in-vitro cardiopulmonary combined perfusion system and a perfusion method. The in-vitro organs are preserved by using an organ perfusion method, ischemia reperfusion injury caused by low-temperature preservation is avoided, and the problem that the in-vitro cardiopulmonary organs cannot be perfused and preserved at the same time is solved. The system comprises an organ cabin, a circulation cabin, a control cabin, a simple breathing cabin, a cardiac pacemaker body, a development and control panel and a base, the organ cabin is connected with the circulation cabin, the control cabin and the simple breathing cabin, and the control cabin is connected with the development and control panel. The organ cabin, the circulation cabin, the control cabin, the simple breathing cabin and the imaging and control panel are installed on the base, the simple breathing machine is placed in the simple breathing cabin, and the simple breathing machine and the cardiac pacemaker are respectively connected with the in-vitro cardiopulmonary to form an in-vitro cardiopulmonary support system. The cardiac pacemaker monitors and outputs a signal to the control cabin, and the control cabin controls the work of the cardiac pacemaker.

Description

technical field [0001] The invention relates to the technical field of organ transplantation, in particular to an isolated heart-lung combined perfusion system and a perfusion method. Background technique [0002] Organ transplantation is an effective means of treating end-stage organ diseases. At present, about 300,000 people are still waiting for organ transplantation, so every donor is very precious, so it is very important to do a good job in perfusion preservation of donors. [0003] With the development of heart and lung transplantation technology, more and more attention has been paid to the protection of donor heart and lung. The preservation quality of donor heart and lung directly affects the survival rate of patients after organ transplantation. At present, in clinical practice, the isolated heart and lungs are mainly preserved by low temperature immersion in organ preservation solution. Storage time in vitro. However, the low temperature storage time is general...

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide an isolated heart-lung combined perfusion system and perfusion method, which uses organ perfusion to preserve isolated organs, avoids ischemia-reperfusion injury caused by low temperature storage, and solves the problem that isolated heart-lung organs cannot be perfused simultaneously At the same time, it also solves the problem of the lack of real anatomical organs in the training of clinicians and the lack of disease models in pathological research

Images