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Collagen dressing containing icodextrin

An icodextrin and sticking technology, applied in the field of medical devices, can solve the problems of inability to protect the film, small molecular weight, weak protective effect, etc., and achieve a good feeling of use

Pending Publication Date: 2020-10-09
HUAREN PHARMACEUTICAL CO LTD +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the molecular weight of α-glucan oligosaccharides is small, so it cannot form an effective protective film on the skin surface, and the protective effect is weak

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Collagen dressing containing icodextrin: icodextrin 0.7%, hydrolyzed collagen 0.4%, pentylene glycol 3.2%, chlorphenesin 0.03%, phenoxyethanol 0.35%, ethylhexylglycerin 0.11%, 1, 2-hexanediol 0.5%, hydroxyethyl cellulose 0.08%, sweet orange essential oil 0.01%, purified water 94.62%.

Embodiment 2

[0029] Collagen dressing containing icodextrin: icodextrin 0.6%, hydrolyzed collagen 0.7%, 1,2-hexanediol 4.1%, chlorphenesin 0.5%, hydroxymethylcellulose 0.09%, peppermint essential oil 0.25% %, purified water 93.76%.

Embodiment 3

[0031] Collagen dressing containing icodextrin: icodextrin 0.8%, hydrolyzed collagen 0.4%, pentylene glycol 2.4%, phenoxyethanol 0.6%, hydroxyl cellulose 1.05%, lavender essential oil 0.02%, purified water 94.73% .

[0032] Collagen dressings containing icodextrin prepared from the above examples and non-woven fabrics by common preparation methods (each dressing contains 10 g of the composition in the examples) were applied to 50 acne patients (excluding collagen allergies) ), during use, take one tablet per day for the first two days, and then apply one tablet every other day, seven days as a course of treatment. During the application process, acne patients feel that the fragrance of the dressing obtained by the present invention is elegant and fresh, and the application process is comfortable, and no symptoms appear. Adverse reactions, acne did not continue to develop after one course of treatment, and were greatly improved after two courses of treatment.

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Abstract

The invention provides a collagen dressing containing icodextrin. The collagen dressing is prepared from icodextrin, hydrolyzed collagen, polyhydric alcohol, a preservative, a thickening agent and a flavoring agent. The collagen dressing is prepared by mixing the raw materials with purified water. The obtained dressing is prepared by combining icodextrin with collagen, is used for closed soft tissues, provides a healthy and clean microenvironment for the skin surface, can provide collagen required by skin recovery and assist the skin to recover more quickly, can be made into a non-woven fabric / gauze + stock solution form, is matched with different fragrances, and is good in use feeling, convenient to use and good in commercialization effect.

Description

technical field [0001] The invention belongs to the field of medical devices, in particular to a collagen dressing containing icodextrin. Background technique [0002] In the medical field, dressings generally refer to external materials that can protect wounds, prevent secondary infection and heat loss. At present, there are mainly traditional gauze dressings and modern dressings. Modern dressings include sodium alginate / calcium dressings, interactive dressings, silver Ionic dressings, foam dressings and gel dressings, etc. [0003] α-glucan oligosaccharide is a product obtained by the action of glucotransferase on maltose. Its polymerization degree is 4 to 6 glucose units, its molecular weight is very small, and its main function is to moisturize. However, the molecular weight of α-glucan oligosaccharides is small, so it cannot form an effective protective film on the skin surface, and the protective effect is weak. [0004] Icodextrin is a kind of dextran obtained by hy...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/02A61K8/33A61K8/34A61K8/65A61K8/73A61K8/92A61P17/10A61Q19/00A61Q19/08
CPCA61K8/73A61K8/65A61K8/33A61K8/34A61K8/345A61K8/731A61K8/922A61K8/0208A61Q19/00A61Q19/08A61P17/10
Inventor 杨效东冯新光班文溥王盈盈
Owner HUAREN PHARMACEUTICAL CO LTD
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