A detection method, detection system and terminal of bacterial flora markers

Abstract

This application is applicable to the field of biotechnology, and provides a detection method, detection system and terminal of bacterial flora markers, wherein the method includes: obtaining bacterial flora sample data; according to the representative sequence of the bacterial taxon, using the phylogenetic tree algorithm , to obtain the similarity between different bacterial species taxa, and obtain the corresponding similarity matrix; according to the sample class label, the abundance of the bacterial taxa to which the different bacterial species belong and the similarity matrix, Through the generalized lasso regression algorithm model, the target regression coefficient vector corresponding to the set fitting effect is obtained; the bacterial classification unit corresponding to the non-zero coefficient element in the target regression coefficient vector is determined as the target flora marker, and the improvement is achieved. Validity of screened flora markers.

Description

technical field [0001] The application belongs to the field of biotechnology, and in particular relates to a detection method, a detection system and a terminal of a flora marker. Background technique [0002] In recent years, with the rapid development of DNA sequencing technology, the cost of DNA sequencing has also been reduced year by year. We can more easily explore the health status of human beings through information at the genetic level. However, the data dimension at the genetic level is often very large, and it is difficult to analyze. When making machine learning predictions, it is prone to the curse of dimensionality. Therefore, it is very important to find meaningful features among the features of massive genetic data. [0003] The structure of the flora is very complex, and the detection of effective flora markers is of great significance for us to explore the structure of the flora and the impact of the flora on human health. [0004] In the prior art, when ...

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Problems solved by technology

[0005] In view of this, the embodiment of the present application provides a detection method, detection system and terminal of flora markers to solve the problem of using only local information of flora when screening effective flora markers in the prior art. In this process, the information is lost, the complex relationship between the flora cannot be fully reflected, and the effectiveness of the screened flora markers is reduced.

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