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Composition for activating protein l-isoaspartate methyltransferase

A composition, protein technology, applied in the fields of drug combination, cosmetics, food science, etc., can solve the problems of skin impact, lack of elasticity, rough skin, etc.

Active Publication Date: 2022-05-03
SUNTORY HLDG LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, internal factors such as the decline of various skin functions with age, and external factors such as ultraviolet exposure can cause skin aging phenomena such as wrinkles, sagging, lack of elasticity, dullness, and rough skin.
In particular, the skin damage caused by ultraviolet rays, which is the main external factor, is cumulative and accelerates the progress of skin aging due to aging, leading to a deeper aging state, which has a significant impact on the skin.

Method used

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  • Composition for activating protein l-isoaspartate methyltransferase
  • Composition for activating protein l-isoaspartate methyltransferase
  • Composition for activating protein l-isoaspartate methyltransferase

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0173] Hereinafter, the Example which can explain this invention more concretely is shown. In addition, this invention is not limited only to these Examples.

[0174] The protein extraction reagent used in the following experiments was manufactured by Thermo Corporation under the trade name of M-PER (registered trademark) Mammalian Protein Extraction Reagent. In the test case, the determination of the significant difference was done by Student's t-distribution test.

manufacture example 1

[0257] lotion

[0258] The raw materials described in Table 6 were stirred until uniform to prepare a lotion for PIMT activation.

[0259] [Table 6]

[0260]

manufacture example 2

[0262] lotion

[0263] The raw materials described in Table 7 were stirred until uniform to prepare an emulsion for PIMT activation.

[0264] [Table 7]

[0265]

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PUM

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Abstract

The object of the present invention is to provide a PIMT activation composition capable of activating protein L-isoaspartate methyltransferase (PIMT), a new index for evaluating skin restoration or repair activity and a new skin anti-aging activity. Index, and the evaluation method of the restoration or repair activity of the skin and the anti-aging activity of the skin using this index. The composition for activating protein L-isoaspartate methyltransferase (PIMT) of the present invention contains a plant selected from Betulaceae Birch, Vitis vinifera, Fabaceae Soybean, Cannabis Humulus, An extract of one or more plants selected from the Labiatae family, Rutaceae citrus plant, Calamus family Calamus plant, Asteraceae Arnica plant, and Rosaceae peach plant.

Description

technical field [0001] The present invention relates to a composition for activating protein L-isoaspartate methyltransferase (PIMT). The present invention also relates to a composition for promoting restoration or repair of a protein containing an isomerized amino acid. The present invention further relates to a method for activating PIMT, and a method for promoting restoration or repair of a protein containing an isomerized amino acid. The present invention also relates to a method for evaluating the restoring or repairing activity of the skin, a method for evaluating the anti-aging activity of the skin, and a method for screening an active ingredient for activation of PIMT present in the skin and the like. Background technique [0002] Keeping skin healthy and youthful is a high concern for most people. However, internal main factors such as the decline of various functions of the skin with age, and external main factors such as UV exposure can cause skin aging such as ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K8/9794A61K36/185A61K36/28A61K36/53A61K36/535A61K36/537A61K36/736A61K36/752A61K36/87A61K36/882A61P17/00A61P43/00A61Q19/08A23L33/105
CPCA23L33/105A61K8/9789A61K8/9794A61K36/185A61K36/28A61K36/53A61K36/535A61K36/537A61K36/736A61K36/752A61K36/87A61K36/882A61P17/00A61P43/00A61Q19/08
Inventor 北川小百合
Owner SUNTORY HLDG LTD
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