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Kit and method for comprehensively evaluating functions of immune cells in human peripheral blood

A technology of immune cells and peripheral blood, applied in the medical field, can solve the problem that there is no real method to evaluate the function and quality of immune cells, and achieve the effect of improving health status, convenient use and simple operation steps.

Inactive Publication Date: 2019-01-22
东莞暨南大学研究院
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  • Summary
  • Abstract
  • Description
  • Claims
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Problems solved by technology

[0003] At present, there is no method that can really evaluate the function and quality of immune cells themselves, including clinical and third-party testing institutions

Method used

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Embodiment Construction

[0025] As used herein:

[0026] "Prepared from" is synonymous with "comprising". As used herein, the terms "comprises," "including," "has," "containing," or any other variation thereof, are intended to cover a non-exclusive inclusion. For example, a composition, step, method, article, or device comprising listed elements is not necessarily limited to those elements, but may include other elements not explicitly listed or inherent to such composition, step, method, article, or device. elements.

[0027] The conjunction "consisting of" excludes any unspecified elements, steps or components. If used in a claim, this phrase will make the claim closed so that it does not contain material other than those described except for the customary impurities associated therewith. When the phrase "consisting of" appears in a clause of the subject of a claim rather than immediately following the subject matter, it only defines the elements described in that clause; other elements are not exc...

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Abstract

The invention provides a kit and a method for comprehensively evaluating functions of immune cells in human peripheral blood. The kit for comprehensively evaluating the functions of the immune cells in the human peripheral blood comprises an anti-human CD3, CD4, CD8, CD19, CD21, CD24, CD25, CD27, CD28, CD38, CD56, CD57, CD94, CD127, CD45RA, CXCR3, CXCR5, CCR4, CCR6, CCR7, HLA-DR, PD-1, P30, P46, NKG2D, KIR (NKB1), gamma delta, v delta 2, IgD and IgM antibodies, wherein the antibodies carry fluorescein labels. The kit can be used for comprehensively evaluating the functions of the immune cellsin the human peripheral blood, and is convenient and safe to use.

Description

technical field [0001] The invention relates to the medical field, in particular to a comprehensive evaluation kit and evaluation method for human peripheral blood immune cell function. Background technique [0002] The immune function of human immune cells is directly related to the occurrence and progression of various diseases. For example, the occurrence and development of tumors are the result of long-term down-regulation or inhibition of the body's own immune cell functions. However, looking at the research literature at home and abroad, it is found that there is currently no method for specifically evaluating the function of immune cells with killing ability in human peripheral blood. At present, the methods used by domestic and foreign clinical and third-party testing institutions to evaluate human immune function are still limited to conventional indicators such as the number and ratio of cells. For example, the blood routine of the hospital only gives the range an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/569
CPCG01N33/56966G01N2333/70503G01N2333/7051G01N2333/70514G01N2333/70517G01N2333/70521G01N2333/70532G01N2333/70539G01N2333/7056G01N2333/70578G01N2333/70589G01N2333/70596G01N2333/715
Inventor 尹芝南吴扬哲
Owner 东莞暨南大学研究院
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