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An experimental device for real-time monitoring of the radial support force of vascular stents in a simulated environment

A technology of radial support and vascular stent, applied in the field of mechanical performance testing of medical devices, can solve the problems of many uncertain factors and low precision, and achieve the effect of controllable flow and temperature

Active Publication Date: 2020-12-11
SOUTHEAST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The accuracy of the anti-parallel plate extrusion performance test and the anti-V-groove extrusion performance test is relatively high, but the stress mode of the stent is different from the actual action mode in the vascular environment, so it can only be an indirect reflection of the radial strength of the stent ; The radial extrusion performance test simulates the actual radial force of the stent in the blood vessel. While obtaining the radial compression force of the stent on the stent, the chronic outstretching force of the stent on the blood vessel can also be obtained at the same time; The anti-hydraulic test can also better simulate the stress shape of the stent in the blood vessel, but the accuracy is low and there are many uncertain factors

Method used

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  • An experimental device for real-time monitoring of the radial support force of vascular stents in a simulated environment
  • An experimental device for real-time monitoring of the radial support force of vascular stents in a simulated environment

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Such as figure 2 In the device shown, the vascular stent 6 selected for testing is a braided and formed WE43 magnesium alloy balloon-expandable degradable vascular stent, and the tightly gripped stent is preloaded on the balloon catheter and delivered to the inner PU transparent elastic tube 7 In the process, the balloon is inflated to the nominal pressure with the filling pressure pump, and the stent squeezes the inner PU transparent elastic tube 7, the nickel-chromium alloy resistance strain wire coil 8, and the outer PU transparent elastic tube 9, and at the same time the stent expands, and the catheter The balloon at the distal end was withdrawn after decompression and contraction. The corrosive medium used was a simulated plasma solution at a temperature of 37°C. The speed of the flow field was controlled by an adjustable-speed peristaltic pump 1. In the corrosive medium fluid, the diameter of the magnesium alloy stent The radial support force decreases with its o...

Embodiment 2

[0043] The device used is the same as that in Example 1, and the vascular stent 6 selected for testing is a self-expanding vascular stent of nickel-titanium shape memory alloy formed by laser engraving. The stent is preloaded on the delivery catheter and placed in the PU transparent elastic tube 7 , connected to the simulated blood circulation device through a silicone hose 5, the corrosive medium used is simulated plasma, the flow field velocity is controlled by an adjustable-speed peristaltic pump 1, and the temperature is adjusted to 37°C to reach the transformation temperature of the alloy, and the stent gradually deforms and expands And to generate support force for the elastic tube, choose constantan wire as the metal resistance strain wire, record the change of the average radial support force during the expansion and retraction process of the stent in real time, and study the influence of blood flow on the radial support force of the vascular stent.

[0044] In order to...

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Abstract

The invention discloses an experimental device for monitoring the radial support force of an intravascular stent in a simulated blood vessel in real-time. The experimental device comprises a variable-speed peristaltic pump (1), a liquid storage tank (2), a water bath box (3), an average stent radial support force monitoring device (4) and silicone hoses (5) connected among all parts. The average stent radial support force monitoring device (4) includes an intravascular stent(6), an inner-layer polymer transparent elastic tube (7), a resistance strain filament type sensor (8), an outer-layer polymer transparent elastic tube (9), a polymer transparent rigid tube (10), a fixation sleeve (11), a data collector (12) and a computer (13). The experimental device is capable of monitoring a radialsupport force applied to a simulated blood vessel by an intravascular stent in a flowing corrosive medium in vitro in real time and is capable of measuring average radial support forces of intravascular stents that are made different materials and have different structures. The experimental device has advantages of simple structure, low cost and great convenience to operate.

Description

technical field [0001] The invention relates to an experimental device for real-time monitoring of the radial support force of a vascular stent in a simulated environment, belonging to the field of mechanical performance testing of medical instruments. Background technique [0002] The radial mechanical properties of vascular stents are mainly reflected in the resistance of vascular stents to external pressure and the strain capacity of vascular stents to external forces. This characteristic determines whether the vascular stent can be tightly attached to the vessel wall. If the supporting force is too small, the lumen of the vascular stent will become smaller under the reaction force of the blood vessel, which will easily cause vascular embolism, and the medical effect of the vascular stent cannot be exerted. Cause local vascular wall damage (such as perforation, tearing, rupture, etc.), causing excessive repair response of surrounding tissues, resulting in intimal hyperpla...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01L9/04
CPCG01L9/04
Inventor 储成林韩林原张真玮白晶薛烽郭超
Owner SOUTHEAST UNIV
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