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Traditional Chinese medicinal extract for treating stomachache, hypochondriac pain, gastroenteric ulcer and depression, as well as preparation methodS and application thereof

An extract, depression technology, applied in the directions of food ingredients, applications, and drug combinations containing natural extracts, can solve the problems of insufficient efficacy, backward technology, unstable quality, etc., and achieve easy processing preparations, large adsorption capacity, heavy good effect

Inactive Publication Date: 2018-11-27
湖北颐仁中医药研究总院有限公司
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Problems solved by technology

Systematically optimize and confirm its main components to solve problems such as unstable quality, backward technology, and insufficient efficacy of traditional preparations

Method used

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  • Traditional Chinese medicinal extract for treating stomachache, hypochondriac pain, gastroenteric ulcer and depression, as well as preparation methodS and application thereof
  • Traditional Chinese medicinal extract for treating stomachache, hypochondriac pain, gastroenteric ulcer and depression, as well as preparation methodS and application thereof
  • Traditional Chinese medicinal extract for treating stomachache, hypochondriac pain, gastroenteric ulcer and depression, as well as preparation methodS and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Embodiment 1 Water extraction method prepares " Hua Gan Jian " side Chinese medicine extract

[0046] Method 1: take green peel, tangerine peel, peony root, peony peel, gardenia (stir-fried), Alisma, and Fritillaria as raw materials, and use water as a solvent to extract the raw materials. The weight ratio of each raw material is green peel: tangerine peel: peony: peony cortex : Gardenia (stir-fried): Alisma: Fritillaria = 4: 4: 4:: 3: 3: 3: 6; cleanly select the above-mentioned medicinal materials, weigh 28 kg of green peel, 28 kg of orange peel, peony 28 kg, 21 kg of Moutan bark, 21 kg of Gardenia, 21 kg of Alisma, 42 kg of Fritillaria, soaked in 1.89 tons of water for 20 minutes, heated and extracted 3 times, the first extraction was 2.5 hours, and the second extraction was 1 hour (the amount of water added Consistent with the first time), the third extraction is 30min (the amount of water added is consistent with the first time), and each extraction time is calculat...

Embodiment 2

[0049] Example 2 Alcohol extraction method to prepare "Huaganjian" side Chinese medicine extract

[0050] Method 1: take green peel, tangerine peel, peony root, peony peel, gardenia (stir-fried), Alisma, and Fritillaria as raw materials, and use 65% ethanol as a solvent to extract the raw materials. The weight ratio of each raw material is green peel: tangerine peel: peony: Cortex Moutan: Gardenia (stir-fried): Alisma: Fritillaria = 4: 4: 4:: 3: 3: 3: 6; cleanly select the above-mentioned medicinal materials, and weigh 28 kg of green peel and 28 kg of tangerine peel , 28 kg of peony, 21 kg of peony cortex, 21 kg of gardenia, 21 kg of Alisma, 42 kg of Fritillaria, soaked in 1.89 tons of 65% ethanol for 20 minutes, heated and extracted 3 times, the first extraction was 2.5 hours, and the second extraction 1h (the amount of alcohol added is the same as the first time), the third extraction is 30min (the amount of alcohol added is the same as the first time), and the extraction ti...

Embodiment 3

[0053] Example 3 Water Extraction and Alcohol Precipitation Method to Prepare "Huaganjian" Chinese Medicine Extract

[0054] Method 1: take green peel, tangerine peel, peony root, peony peel, gardenia (stir-fried), Alisma, and Fritillaria as raw materials, and use water as a solvent to extract the raw materials. The weight ratio of each raw material is green peel: tangerine peel: peony: peony cortex : Gardenia (stir-fried): Alisma: Fritillaria = 4: 4: 4:: 3: 3: 3: 6; cleanly select the above-mentioned medicinal materials, weigh 28 kg of green peel, 28 kg of orange peel, peony 28 kg, 21 kg of Moutan bark, 21 kg of Gardenia, 21 kg of Alisma, 42 kg of Fritillaria, plus 1.89 tons: soak in 1 ton of water for 20 minutes, heat extraction for 3 times, the first extraction for 2.5 hours, the second extraction for 1 hour (the amount of water added is the same as the first time), the third extraction is 30min (the amount of water added is the same as the first time), the extraction time ...

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Abstract

The invention provides a traditional Chinese medicinal extract for treating stomachache, hypochondriac pain, gastroenteric ulcer and depression, as well as six preparation methods and application thereof. The traditional Chinese medicinal extract is prepared from the following raw materials: pericarpium citri reticulatae viride, pericarpium citri reticulatae, peony, moutan bark, cape jasmine (roasted), rhizoma alismatis and rhizoma bolbostemmae in a weight ratio of 4:4:4:3:3:3:6. The six preparation methods include (1) water extraction method; (2) alcohol extraction method; (3) water extraction and alcohol precipitation method; (4) water extraction combined macroporous resin purification method; (5) alcohol extraction combined macroporous resin purification method; and (6) classic decoction preparation method (classic prescribed substance standard). According to the preparation methods, the extract process is optimized to prepare traditional Chinese medicinal preparations, and the mainingredient of active parts can be defined. The traditional Chinese medicinal extract oral preparation, namely the formula of liver-depressed and gastropyretic epigastralgia, is provided, the preparedproduct is detected to reflect clear and definite active substance foundation and relatively high content of the traditional Chinese medicinal extract, namely the formula of liver-depressed and gastropyretic epigastralgia.

Description

technical field [0001] The invention relates to a traditional Chinese medicine extract (hereinafter also called Huagan decoction extract) for treating stomach pain, hypochondriac pain, gastrointestinal ulcer and depression, its preparation method and application, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Traditional Chinese medicine is the quintessence of my country. It has a history of thousands of years of application in our country, especially from the classics such as "Jingyue Quanshu", "Treatise on Febrile Diseases", "Taiping Huimin Hejiju Prescription", "Golden Chamber Synopsis" and so on. Famous prescriptions, after nearly a thousand years of clinical experiments, have been widely proven to be scientifically effective, so they have been passed down and flourished for a long time. Compared with modern traditional Chinese medicine preparations, traditional preparations generally have disadvantages such as backward t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/884A61P1/00A61P1/04A61P25/24A23L33/105
CPCA23L33/105A23V2002/00A61K36/42A61K36/65A61K36/71A61K36/744A61K36/752A61K36/884A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61P1/00A61P1/04A61P25/24A61K2300/00A23V2200/32A23V2250/21
Inventor 严启新傅庆林曾琪傅勃
Owner 湖北颐仁中医药研究总院有限公司
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