Pharmaceutical microorganism identification method

An identification method and technology of microorganisms, which are applied in biochemical equipment and methods, measurement/inspection of microorganisms, enzymology/microbiology devices, etc., can solve problems such as clogging of filter membranes and inability to continue experiments, so as to improve efficiency and benefit Survival, the effect of simple methods

Active Publication Date: 2018-06-29
SUZHOU ABOGEN BIOSCIENCES CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are certain defects in this technology at present. Some drug test solutions contain carbomer, cellulose derivatives, colloidal silicon, calcium soap and insoluble drug residues, etc., which often block the filter membrane during the test process, making the test unable to continue.

Method used

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  • Pharmaceutical microorganism identification method
  • Pharmaceutical microorganism identification method
  • Pharmaceutical microorganism identification method

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0035] Step 2: Preparation of drug solution: add distilled water to the drug, make it fully dissolve and mix to form a drug solution, and then add the drug solution into the identification cylinder 1;

[0036]Step 3: Preparation of identification reagents: prepare the reagents required for drug solution identification into liquid identification reagents for later use, then put the liquid identification reagents and identification cylinder 1 together in an air-conditioned room with a temperature of 20-25 degrees Celsius for 2 hours;

[0037] Step 4: Add liquid: control the connecting piece to fix the stirring shaft 32, shake the handle, make the liquid adding rod 41 and the stirring shaft 32 relatively fixed through thread fit, and pour the liquid identification reagent from the No. 1 through hole in the center of the liquid adding rod 41 In the identification cylinder 1, the liquid identification reagent and the drug solution are mixed;

[0038] Step 5: Mix liquid: control the...

Embodiment approach

[0044] As an embodiment of the present invention, the connector 51 includes an outer ring 516, a No. 2 electromagnet 517, a No. 2 spring 518, rubber 519 and an inner ring 520. The outer ring 516 is circular, and the outer ring 516 Installed on the base 2, the inner surface of the outer ring 516 offers No. 4 groove, No. 2 electromagnet 517 is installed at the bottom of No. 4 groove, and the other end of No. 2 electromagnet 517 is connected with No. 2 spring 518 horizontally. The other end is connected to the rubber 519; the inner ring 520 is arranged at the center of the outer ring 516, the inner ring 520 is circular, the outer side of the inner ring 520 is connected with the rubber 519, and the inner side of the inner ring 520 is connected with the stirring shaft 52 connect. During work, by controlling No. 2 electromagnet 517, No. 2 electromagnet 517 drives No. 2 spring 518 to extrude rubber 519, and rubber 519 extrudes inner ring 520 inwardly. At this time, inner ring 520 and...

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PUM

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Abstract

The invention belongs to the technical field of microorganism examination, and more specifically discloses a pharmaceutical microorganism identification method. An identification device is adopted inthe pharmaceutical microorganism identification method. The pharmaceutical microorganism identification method comprises following steps: preparation of an identifying agent, preparation of a drug solution, liquid adding, liquid mixing, and observing. In identification process, a stirring module of the identification device is used for full mixing of the drug solution with the identifying agent, so that development of different colors of microorganisms in the drug solution under the action of the identifying agent is realized, and identification of the varieties of the microorganisms in the drug solution is realized. The pharmaceutical microorganism identification method is simple; operation is convenient; identification results are visual and obvious; and identification efficiency and identification result accuracy are increased.

Description

technical field [0001] The invention belongs to the field of drug microbiology testing, in particular to a drug microbiological identification method. Background technique [0002] Microbial contamination is one of the main causes of adverse drug events. Preventing contaminated drugs from entering the market is of great significance for ensuring the safety of patients. In the microbiological inspection of pharmaceuticals, whether the microorganisms in the microscopic world can be detected, the inspection method is intuitive and important. Membrane filtration technology is an important technology for collecting microorganisms in the field of pharmaceutical microbial inspection. For drugs with antibacterial activity, it is necessary to use membrane filtration to fully eliminate the antibacterial activity of the drug, so as to facilitate the recovery, reproduction and detection of dormant or damaged microorganisms in the drug. However, there are certain defects in this techno...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/00C12M1/02C12Q1/04A61L2/10
CPCA61L2/10C12Q1/04
Inventor 郭庆张瑞周军鹏
Owner SUZHOU ABOGEN BIOSCIENCES CO LTD
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