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neuroprotective agent

A neuroprotective agent and solvent technology, applied in the field of neuroprotective agents, can solve the problems of no nerve function recovery treatment drugs, no nerve cell protective agents, etc.

Active Publication Date: 2019-02-12
SOUTH UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, at present, there are no other effective nerve cell protective agents, and no therapeutic drugs that can promote the recovery of neurological function, except for the very limited clinical time window of the drugs for the treatment of stroke.

Method used

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Examples

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Embodiment

[0046] 1. Detection of (-)-PA Existence of High Level Endogenous in Mouse Brain

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Abstract

A neuroprotective agent, comprising a compound as represented by formula (I).

Description

technical field [0001] The invention relates to the field of medicines, in particular to a neuroprotective agent. Background technique [0002] Stroke has become one of the three major diseases that seriously endanger human health. However, at present, there are no other effective nerve cell protective agents, and no therapeutic drugs that can promote the recovery of neurological function, except for the antithrombotic drugs that are used in a very limited clinical time window in the clinical treatment of stroke. Despite decades of efforts, the understanding of endogenous neuroprotective molecules and mechanisms induced by stroke is still limited (Molecular mechanisms of cerebralischemia-induced neuronal death. Hou ST, MacManus JP (2002), Int Rev Cytol 221:93 -148.; The science of stroke: mechanisms in search of treatments. Moskowitz MA, LoEH, Iadecola C (2010). Neuron67:181-198). [0003] Phaseic acid (Phaseic Acid, PA) is the catabolism product of abscisic acid (ABA) ter...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/343A61K47/42A61P25/00A61P9/10
CPCA61K31/343A61K47/42A61P9/10A61P25/00
Inventor 侯圣陶
Owner SOUTH UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA
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