Traditional Chinese medicine composition for externally treating skin rash, and preparation method and application of traditional Chinese medicine composition

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine, can solve the problems such as the treatment cannot be carried out normally, the effect of tumor treatment is affected, and the effect is not obvious.

Active Publication Date: 2015-11-25
CHINA JAPAN FRIENDSHIP HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Acne / acne-like rash not only affects the quality of life of patients, but also may lead to the failure of normal treatment, seriously affecting the therapeutic effect of tumors
Acne / acneoid rash limits the application of EGFRIs to some extent
Western medicine often uses antibiotics, external hormones and other methods of treatment, the effect is not very obvious

Method used

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  • Traditional Chinese medicine composition for externally treating skin rash, and preparation method and application of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for externally treating skin rash, and preparation method and application of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for externally treating skin rash, and preparation method and application of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Prescription: Scutellaria baicalensis 20g, purslane 30g, white moss bark 30g, flavescens 20g, dandelion 30g, red peony 15g, mint 5g;

[0064] Preparation method: Take the raw material according to the proportion, decoct it twice, combine the extracts, filter, concentrate under reduced pressure to a density of 1.10 (60°C), centrifuge at a high speed, and take the supernatant; according to the supernatant: glycerol: density = 2.2 : Add excipients at a ratio of 1:2 to make external preparations.

[0065] Usage: Apply directly to the rash area or make a mask and stick it on the face.

Embodiment 2

[0067] Prescription: Scutellaria baicalensis 25g, purslane 40g, white moss bark 35g, flavescens 30g, dandelion 35g, red peony 17g, mint 4g;

[0068] Preparation method: take the raw material drug in proportion, extract twice with 50% ethanol under reflux, combine the extracts, filter, recover ethanol, add water to dissolve, concentrate under reduced pressure to a density of 1.10 (60°C), centrifuge at a high speed, and take the supernatant; according to the above Serum: Glycerin: Density = 2.2:1:2 The ratio is added with excipients to make external preparations.

[0069] Usage: Apply directly to the rash area or make a mask and stick it on the face.

Embodiment 3

[0071] Prescription: Scutellaria baicalensis 30g, purslane 35g, white moss bark 40g, flavescens 25g, dandelion 40g, red peony 12g, mint 6g;

[0072] The preparation method is the same as in Example 1.

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Abstract

The invention provides a traditional Chinese medicine composition for externally treating skin rash. The traditional Chinese medicine composition comprises the following raw herbal materials in part by weight: 10-50 parts of radix scutellariae, 10-60 parts of purslane, 10-60 parts of cortex dictamni, 10-50 parts of sophora flavescens, 10-60 parts of dandelion, 5-30 parts of red peony root and 1-10 parts of mechanism. The traditional Chinese medicine composition has an obvious effect of improving EGFRIs (epidermal growth factor receptor inhibitors) relevant acneiform rash and itch degree, and untoward effects do not exist.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and its preparation method and application, in particular to an external Chinese medicinal composition for treating skin rashes, its preparation method and application, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] In recent years, the clinical application of tumor targeted therapy has been increasing year by year, and its therapeutic effect is also increasing. It will soon become a promising tumor treatment method in the 21st century. Epidermal growth factor receptor antagonists (EGFRIs) are the most widely used clinically at present. These drugs are favored by doctors and patients for their outstanding clinical efficacy. However, its adverse reactions have various manifestations, among which rash (mainly acne / acneoid rash) is the most common. Acne / acne-like rash not only affects the quality of life of patients, but also may lead to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/75A61P17/00
Inventor 崔慧娟
Owner CHINA JAPAN FRIENDSHIP HOSPITAL
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