Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A Method for Obtaining Two-Dimensional Spin Echo Correlation Spectrum of NMR under Inhomogeneous Magnetic Field

A spin echo and uniform magnetic field technology, applied in the field of nuclear magnetic resonance spectroscopy, can solve problems such as the application of the two-dimensional SECSY method, achieve a simple and effective method, and overcome the effect of uneven magnetic field

Active Publication Date: 2016-01-20
XIAMEN UNIV
View PDF4 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] It can be seen that the unideal magnetic field conditions limit the application of two-dimensional SECSY spectrum. Although there have been a series of hardware or software shimming methods to improve the uniformity of the magnetic field, due to its own limitations, there is no way to make the two-dimensional SECSY method applicable. to an unfavorable magnetic field environment

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A Method for Obtaining Two-Dimensional Spin Echo Correlation Spectrum of NMR under Inhomogeneous Magnetic Field
  • A Method for Obtaining Two-Dimensional Spin Echo Correlation Spectrum of NMR under Inhomogeneous Magnetic Field
  • A Method for Obtaining Two-Dimensional Spin Echo Correlation Spectrum of NMR under Inhomogeneous Magnetic Field

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment

[0037] This new method scans a conventional chemical sample solution as an example, and uses this specific example to verify the feasibility of the present invention. The samples used in the experiment were butyl methacrylate (CH 2 C(CH 3 ) COOCH 2 CH 2 CH 2 CH 3 , solute) in DMSO ((CH 3 ) 2 SO, solvent) solution, the experimental test was carried out under a Varian 500MHz NMR spectrometer (Varian, PaloAlto, CA), and no artificial shimming operation was performed during the whole experimental process. According to the operation flow of the high-resolution two-dimensional spin-echo correlation spectrum method above, firstly a one-dimensional spectrum is obtained by sampling with a conventional simple one-dimensional pulse sequence, and the sampling time is 2s. The result is as follows figure 2 As shown, the spectral line width of 120 Hz can be obtained from this one-dimensional spectrum. Since the sample is directly sampled without shimming, the uniformity of the magnet...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

A method for obtaining a nuclear magnetic resonance two-dimension spin echo related spectrum under an uneven magnetic field relates to a nuclear magnetic resonance wave spectrum detection method and comprises the steps of using a normal one-dimension pulse sequence to sample a one-dimension spectrum, obtaining the line width of spectral lines, and providing a basis for spectrum width parameter setting, wherein the line width value also reflects the uniformity condition of a magnetic field; introducing well precompiled two-dimension spin echo related spectrum pulse sequences onto a nuclear magnetic resonance spectrometer; opening a multi-quantum coherent signal selection module, a three-dimension sampled indirect dimension evolution period t1 combination and indirect dimension evolution period t2 combination and an echo delay module among the two-dimension spin echo related spectrum pulse sequences; setting each experiment parameter of the two-dimension spin echo related spectrum pulse sequences; executing the two-dimension spin echo related spectrum pulse sequences, of which the experiment parameters are set, for data sampling; after the data sampling is finished, performing related data postprocessing to obtain the two-dimension spin echo related spectrum uninfluenced by the uneven magnetic field. The method has no need of shimming operation and is simple, convenient and effective.

Description

technical field [0001] The invention relates to a nuclear magnetic resonance spectroscopy detection method, in particular to a method for obtaining a high-resolution nuclear magnetic resonance two-dimensional spin echo correlation spectrum under an inhomogeneous magnetic field. Background technique [0002] Two-dimensional spin echo correlation spectroscopy (Spin-EchoCorrelated SpectroscopY, SECSY) is one of the earliest proposed two-dimensional spectroscopy methods in the field of NMR. The conventional SECSY sequence is composed of a π / 2 pulse, a π pulse, and an indirect dimensional evolution period t divided in half 1 and a sampling period t 2 constitute. This conventional SECSY method was proposed by Ernst in 1979 (AueW.P., BartholdiE., and ErnstR.R.Two-dimensionalspectroscopyapplicationtonuclearmagneticresonance[J].J.Chem.Phys.,1976,64,2229-2246), Usually a two-dimensional SECSY spectrum contains principal component peaks and cross peaks, where the principal component...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): G01R33/565
Inventor 黄玉清陈忠
Owner XIAMEN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com