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Applications of root and peel extract products of magnolia delavayi, southern magnolia, magnolia liliiflora and michelia alba

A technology of magnolia magnolia and purple magnolia, applied to medical preparations containing active ingredients, drug combinations, plant raw materials, etc.

Inactive Publication Date: 2014-03-12
龙海波
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, there are no reports on the application of root bark extracts derived from Magnolia magnanii, Magnolia magnate, Purple Magnolia, and White Magnolia in the prevention, treatment or adjuvant treatment of diabetes and chronic complications of diabetes

Method used

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  • Applications of root and peel extract products of magnolia delavayi, southern magnolia, magnolia liliiflora and michelia alba
  • Applications of root and peel extract products of magnolia delavayi, southern magnolia, magnolia liliiflora and michelia alba
  • Applications of root and peel extract products of magnolia delavayi, southern magnolia, magnolia liliiflora and michelia alba

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Embodiment 1: Extract total sesquiterpene lactones from the root bark of Magnolia japonica

[0021] Take 1 kg of dry root bark of Magnolia japonica, and grind it into powder. Get the pulverized coarse powder, extract 3 times with 10 times (weight) of 95% ethanol in reflux, each time for 3 hours. Filtrate, combine the filtrates, and recover the solvent under reduced pressure to obtain the extract. The extract was dissolved with 20% ethanol, then extracted with ethyl acetate until the color of the extract became lighter, the organic solvent was combined, the solvent was recovered under reduced pressure, and dried to obtain 114 grams of solid total sesquiterpene lactones.

Embodiment 2

[0022] Embodiment 2: extract total sesquiterpene lactones from the root bark of Magnolia

[0023] Take 1 kg of dry root bark of Magnolia Magnolia, and grind it into powder. Get the pulverized coarse powder, extract 3 times with 10 times (weight) of 95% ethanol in reflux, each time for 3 hours. Filtrate, combine the filtrates, and recover the solvent under reduced pressure to obtain the extract. The extract was dissolved with 20% ethanol, then extracted with ethyl acetate until the color of the extract became lighter, the organic solvent was combined, the solvent was recovered under reduced pressure, and dried to obtain 96 grams of solid total sesquiterpene lactones.

Embodiment 3

[0024] Example 3: Extracting total sesquiterpene lactones from the root bark of Magnolia japonica

[0025] Take 1 kg of dry root bark of Magnolia japonica, and crush it into powder. Get the pulverized coarse powder, extract 3 times with 10 times (weight) of 95% ethanol in reflux, each time for 3 hours. Filtrate, combine the filtrates, and recover the solvent under reduced pressure to obtain the extract. The extract was dissolved with 20% ethanol, then extracted with ethyl acetate until the color of the extract became lighter, the organic solvent was combined, the solvent was recovered under reduced pressure, and dried to obtain 102 grams of solid total sesquiterpene lactones.

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PUM

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Abstract

The invention relates to applications of root and peel extract products of magnolia delavayi, southern magnolia, magnolia liliiflora and michelia alba, belongs to the technical field of medicine, and specifically relates to the root and peel extract products of magnolia delavayi, southern magnolia, magnolia liliiflora and michelia alba in prevention, curing and adjuvant therapy of diabetes, and diabetes chronic complications, and applications of the root and peel extract products of magnolia delavayi, southern magnolia, magnolia liliiflora and michelia alba in medicines used for prevention, curing and adjuvant therapy of diabetes, and diabetes chronic complications.

Description

technical field [0001] The invention belongs to the technical field of medicines, in particular, it relates to the application of root bark extracts derived from Magnolia magnolia, Magnolia magnolia, Magnolia magnolia, and Magnolia japonica in the prevention, treatment or adjuvant treatment of diabetes and chronic complications of diabetes; Application of the root bark extracts of magnolia magnate, magnolia magnolia, purple magnolia and white magnolia in the preparation of medicines for preventing, treating or assisting the treatment of diabetes and chronic complications of diabetes. Background technique [0002] With the improvement of living standards, population aging, and changes in lifestyle, the prevalence of diabetes mellitus (DM) has increased rapidly, and it has become the third largest non-communicable disease in developed countries after cardiovascular disease and tumors. The incidence of DM in my country is also increasing year by year. According to statistics, t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/575A61P3/10A61K125/00
Inventor 龙海波
Owner 龙海波
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