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Drug eluting balloon for the treatment of stenosis and method for manufacturing the balloon

一种球囊、药物的技术，应用在医药配方、药物输送、胶囊输送等方向，能够解决损失药物等问题

Inactive Publication Date: 2013-08-21
INVATEC TECH CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it has been found that when immersed in a blood environment, such balloons may partially lose a certain amount of drug before reaching their final destination, as the folds tend to open or plasma tends to capillary to the lumen beneath the folds

Method used

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  • Drug eluting balloon for the treatment of stenosis and method for manufacturing the balloon
  • Drug eluting balloon for the treatment of stenosis and method for manufacturing the balloon
  • Drug eluting balloon for the treatment of stenosis and method for manufacturing the balloon

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0063] Referring to the drawings, an angioplasty balloon indicated by numeral 1 is mounted at the distal end of catheter 2 .

[0064] The catheter 2 also comprises an elongated tubular body 3 provided with a plurality of lumens 4, 4' (for a guide wire and a channel for inflating or deflating the balloon, respectively), and at its proximal end a connector means 5 . In the figures, the lumens 4, 4' are positioned side by side, but a coaxial arrangement is also conceivable.

[0065] The balloon 1 is adapted to adopt alternatively a deployed configuration and a deflated configuration. The balloon assumes the expanded configuration by injection of pressurized inflation fluid, and conversely, the balloon assumes the deflated configuration by suction of the same inflation fluid.

[0066] The angioplasty balloons of the present invention may be fabricated from any polymeric material conventionally used for these applications, such as, but not limited to, polyamide materials, blends ...

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PUM

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Abstract

A drug eluting angioplasty balloon (1, 101) suitable to adopt a deployed configuration and a collapsed configuration, the balloon having an outer wall (10) disposed around a core (11) defining an axis (X). The balloon (1, 101) comprising in the collapsed configuration a plurality of folds (12, 12', 112) that are laid in a tangential direction about the core (11) and form a plurality of cavities (13a, 13b, 113) loaded with a drug (14), the cavities (13a, 13b, 113) are comprised between the folds (12, 12', 112), wherein the folds (12, 12', 112) originates from distinct longitudinal lines (25, 25', 125, 125') along the outer wall (10), are arranged in pairs and are circumferentially wrapped about the core (11) in such a way that a fold of one pair overlaps an adjacent fold of another pair and are wrapped in opposite directions.

Description

technical field [0001] The present invention relates to balloon catheters for angioplasty and pharmacological treatment of stenosis. The invention also relates to a method for manufacturing said balloon catheter. Background technique [0002] Balloon catheters for the angioplasty treatment of strictures in the human circulatory system have long been known. These catheters include a balloon at their distal end. Balloon catheters are inserted into a blood vessel with a balloon in a deflated configuration, close to the site of the stenosis. At this point, the balloon is inflated in a relatively short span of time to achieve dilation of the vessel and concomitant mechanical treatment of the stenosis, which is appropriate to restore that segment of vessel. However, in some patients, this mechanical action can cause excessive proliferation of cells called restenosis at the intervention site, which in turn can lead to embolization of blood vessels with serious consequences for t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M29/02A61M25/00
CPCA61L29/16A61L2300/416A61L2300/62A61L2300/63A61M25/1011A61M25/1038A61M25/104A61M2025/1004A61M2025/1031A61M2025/105A61M2025/1052
Inventor M·莫里罗G·斯卡尔维尼
Owner INVATEC TECH CENT
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