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Blood analyzer, blood analysis method, and computer program product

A technology of blood analysis and packaging, which is applied in the direction of measuring devices, analysis materials, individual particle analysis, etc., and can solve the problems of distinguishing and detecting abnormal lymphocytes and abnormal lymphocytes that are not mentioned

Active Publication Date: 2012-11-07
SYSMEX CORP
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, neither Japanese Patent Laid-Open No. 2007-263894 nor Japanese Patent Laid-Open No. 2010-237147 mentions methods for distinguishing and detecting atypical lymphocytes and abnormal lymphocytes

Method used

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  • Blood analyzer, blood analysis method, and computer program product
  • Blood analyzer, blood analysis method, and computer program product
  • Blood analyzer, blood analysis method, and computer program product

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[0278] In the sample preparation part 22, when the blood sample is mixed with the first reagent and the second reagent, and when the blood sample is mixed with the third reagent and the fourth reagent, the respective reaction temperature and reaction time can be adjusted according to the blood cells in the blood sample. The degree of damage and the state of dyeing are appropriately set, and there are no special restrictions. Specifically, adjustment can be made such that the reaction time is shortened when the reaction temperature is high, and the reaction time is prolonged when the reaction temperature is low. More specifically, the mixing of the blood sample and the reagent is preferably carried out at a temperature of 20°C-45°C for 3-40 seconds.

[0279] In the above embodiment, the second measurement process was performed using the third reagent containing a hemolytic agent and the fourth reagent containing a fluorescent dye capable of staining nucleic acid, but the presen...

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Abstract

A blood analyzer, a blood analysis method, and a computer program product that can distinguishably detect abnormal lymphocytes, blasts, and atypical lymphocytes are provided. A blood analyzer prepares a first measurement sample from a first reagent containing a hemolyzing agent, a second reagent containing a fluorescence staining dye, and the blood specimen, and prepares a second measurement sample from a third reagent containing a hemolyzing agent, a fourth reagent containing a fluorescence staining dye, and the blood specimen. The blood analyzer measures each of the measurement samples, and distinguishably detects abnormal lymphocytes, blasts, and atypical lymphocytes in a blood specimen based on the measurement data.

Description

technical field [0001] The present invention relates to a blood analysis device, a blood analysis method, and an information processing device for optically measuring a blood sample and classifying blood cells contained in the blood sample. Background technique [0002] There are five types of white blood cells in normal peripheral blood: lymphocytes, monocytes, basophils, eosinophils, and neutrophils. Most blood cell counting devices have the ability to divide the white blood cells in blood samples into the above Five categories of functions. On the other hand, in diseases such as viral infections and hematopoietic organ tumors, cells that do not exist in normal peripheral blood appear. Abnormal leukocytes appearing in peripheral blood include abnormal monocytes, and such abnormal monocytes can be broadly classified into reactive and neoplastic. Reactive abnormal monocytes such as "atypical lymphocytes" are common in conditions such as viral infection or drug allergy. Ne...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N21/00
CPCG01N21/51G01N2021/4707G01N2021/6441G01N15/1459G01N35/026G01N2021/4726G01N2035/0415G01N2015/1006G01N15/14
Inventor 安部壮纪吉田步林森·乔·约阿希姆·路易莎·玛利亚
Owner SYSMEX CORP
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