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Full-automatic hybridization appliance

A hybridization instrument, fully automatic technology, applied in the field of medical devices, can solve the problems affecting the results and use effects of gene chips, complex washing and color development steps, labor-intensive and time-consuming, etc. The effect of precise cost and positioning accuracy

Active Publication Date: 2012-07-04
亚能生物技术(深圳)有限公司
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Problems solved by technology

[0005] The technical problem mainly solved by the present invention is that in the prior art, the operation of the membrane washing and color development steps in the process of using the gene chip is complicated, which needs to consume a lot of manpower and time, and because there are many operating steps, errors or errors caused by human factors are easy to occur , affecting the result and use effect of the gene chip, a fully automatic hybridization instrument is proposed

Method used

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Embodiment Construction

[0023] In order to describe the technical content, structural features, achieved goals and effects of the present invention in detail, the following will be described in detail in conjunction with the embodiments and accompanying drawings.

[0024] see figure 1 , the present invention provides a fully automatic hybridization instrument, comprising a hybridization platform 1, a frame 3, and a backboard 2, the frame 3 and the backplane 2 are fixed on the hybridization platform 1, and the hybridization platform 1 is provided with Reagent supply device 10 comprises A liquid reagent bottle 107, B liquid reagent bottle 105, C liquid reagent bottle 108, aluminum box A liquid reagent bottle 106, clear water reagent bottle 103, POD reagent bottle 102, waste liquid reagent bottle 101, color development Liquid reagent bottle 104, reagent preheating device, comprises the B liquid heating outer bladder 1051 that is used to preheat reagent in B liquid reagent bottle 105, the A liquid heatin...

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Abstract

The invention discloses a full-automatic hybridization appliance, which comprises a hybridization platform, a machine frame and a back plate. The machine frame and the back plate are fixed on the hybridization platform which is provided with a reagent supply device and a reagent preheating device, wherein the reagent supply device is matched with the reagent preheating device. The machine frame is provided with a hybridization reaction box, a feeding device for feeding reagent in the reagent supply box into the reaction box, an X-axis synchronous belt mechanism for driving the feeding device to reciprocate along the X-axis direction, a Z-axis synchronous belt mechanism for driving the feeding device to reciprocate along the Z-axis direction and a Y-axis synchronous belt mechanism for driving the hybridization reaction box to reciprocate along the Y-axis direction. The full-automatic hybridization appliance can achieve full-automatic operation of steps of washing, hybridizing, enzyme incubation, developing and the like in the gene chip operation technology, is low in manual participation, can greatly reduce production cost and effectively pushes generalized and wide application of gene chips.

Description

technical field [0001] The invention relates to the field of medical instruments, in particular to an automatic hybridization instrument. Background technique [0002] Gene chip technology was invented in the mid-to-late 1990s. Until today, it is still an advanced molecular biology technology. This technology can realize high-throughput, fast and sensitive detection of genes and their expression. It is easy to control, but it is difficult to apply and promote. The gradual promotion in the field of genetic testing such as clinical testing was officially started after 2004, and it has developed rapidly in the past two years. At present, the application fields of gene chip technology mainly include gene expression profile analysis, new gene discovery, gene mutation and polymorphism analysis, genome library mapping, disease diagnosis and prediction, drug screening, gene sequencing, etc.; Significant contributions will be made to food supervision, environmental protection, and j...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/00C12M1/38C12M1/34
Inventor QU JINGLIAO SHENGYUNZHANG HAIXULI LEIHUANG SHENGQINGREN WEI
Owner 亚能生物技术(深圳)有限公司
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