Oil-in-water emulsion with high content of oil phase and cleaning effect, preparation method thereof and application
An oil-in-water emulsion and emulsion technology, applied in skin care preparations, pharmaceutical formulas, cosmetic preparations, etc., can solve the problems of high packaging cost and weak decontamination ability of solvent-based products, and achieve significant re-emulsification ability and packaging The effect of low requirements, good flushing and stability
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Embodiment 1-5
[0036] The formulations of Examples 1-5 are shown in Table 1 below.
[0037] Table 1
[0038]
[0039] The oil-in-water emulsions of Examples 1-5 were prepared according to the following steps:
[0040] 1). Dissolve glycerin and chloroacetamide preservatives in water to form a water phase, and then add an oil-in-water emulsifier (that is, cetearyl polyoxyethylene (15) ether and glyceryl stearate) and detergents (i.e., cocamidopropyl betaine, octyl / decylamidopropyl betaine, disodium lauryl sulfosuccinate, N-cocamidoethyl-N-hydroxyethyl Aminodiacetate disodium or N-cocoamidoethyl-N-hydroxyethylaminoacetate) were added to the entire water phase obtained by each formula, and heated to 80 ° C to dissolve to obtain a homogeneous water phase mixture, That is, phase B;
[0041] 2). Mix ethylhexyl palmitate and di-ethylhexyl carbonate to obtain the oil phase, that is, phase A, and then add phase A to phase B obtained in step 1) within 5 minutes under stirring at 800rpm (that is,...
Embodiment 6
[0053] The formulation of Example 6 is shown in Table 2 below.
[0054] Table 2
[0055]
[0056] The oil-in-water emulsion of Example 6 was prepared according to the following steps:
[0057] 1). Dissolve glycerin, xanthan gum and chloroacetamide preservatives in water to form a water phase, then add the oil-in-water emulsifier and detergent into the resulting entire water phase, and heat to 80°C to dissolve to obtain a homogeneous The aqueous phase mixture of the phase, that is, the B phase;
[0058] 2). Mix ethylhexyl palmitate and di-ethylhexyl carbonate to obtain the oil phase, that is, phase A, and then add phase A to phase B obtained in step 1) within 3 minutes under stirring at 800rpm (that is, adding an oil phase accounting for 18wt.% of the total amount of the emulsion per minute), the entire system remains in a uniform emulsified state throughout the addition process; and
[0059] 3). After all the oil phase A is added, increase the stirring speed to 1000rpm f...
Embodiment 7
[0063] The formulation of Example 7 is shown in Table 3 below.
[0064] table 3
[0065]
[0066] The oil-in-water emulsion of Example 7 was prepared according to the following steps:
[0067] 1). Dissolve the chloroacetamide preservative in water to form a water phase, then add the oil-in-water emulsifier and detergent into the resulting entire water phase, and heat to 80°C to dissolve to obtain a homogeneous water phase mixture, That is, phase B;
[0068] 2). Mix ethylhexyl palmitate and di-ethylhexyl carbonate to obtain the oil phase, that is, phase A, and then add phase A to phase B obtained in step 1) within 15 minutes under stirring at 600 rpm (that is, add the oil phase that accounts for 5.7wt.% of the total amount of emulsion per minute), the whole system maintains a uniform emulsified state throughout the addition process; and
[0069] 3). After all the oil phase A is added, turn on the homogenizer for homogenization to obtain the oil-in-water emulsion product, na...
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