Pine pollen and cyclodextrin composition, method for preparing same, use of same in preparation of health-care products for resisting fatigue and improving immunity of organisms
A technology of cyclodextrin and pine pollen, which is applied in the direction of drug combinations, medical preparations of non-active ingredients, anti-toxins, etc., can solve the problems of poor elastic formability of fibrous particles, easy deterioration of raw materials and preparations, and poor dissolution and dispersibility of products. High-level problems, to achieve fine and uniform particle size, improve the body's immunity, eliminate oxidation and bacterial infection
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Embodiment 1
[0053] Example 1, mix 450 grams of broken wall pine pollen with 450 grams of β-cyclodextrin, add 2000 milliliters of water and mix evenly, stir and grind for 2 hours, then dry under reduced pressure at 50°C for 10 hours, pulverize, and pass through a 100-mesh sieve to obtain About 900 grams of powdery solid clathrate.
[0054] Gained solid clathrate adds auxiliary material (10% of prescription total amount): 40 grams of microcrystalline cellulose, 45 grams of sodium starch glycolate, 5 grams of citric acid, 10 grams of fructose; The clathrate was thoroughly mixed, dry granulated, and then compressed into tablets to obtain 1000 pine pollen chewable tablets (1000 mg / tablet, broken wall pine pollen content: 450 mg / tablet).
Embodiment 2
[0055] Example 2, mix 500 grams of broken wall pine pollen with 300 grams of β-cyclodextrin, add 2000 milliliters of water and mix evenly, stir and grind for 2 hours, then dry under reduced pressure at 50°C for 10 hours, pulverize, and pass through a 100-mesh sieve to obtain About 800 grams of powdery solid clathrate.
[0056] The obtained solid clathrate was added with the following auxiliary materials: 20 grams of microcrystalline cellulose, 40 grams of starch, 35 grams of sodium starch glycolate, and 5 grams of magnesium stearate; after the various auxiliary materials were fully mixed, take 2 / 3 of the auxiliary materials and solid Mix the clathrate, mix thoroughly, moisten the soft material with 70% ethanol, pass through a 14-mesh sieve to granulate, dry at 50°C for 2 hours, add another 1 / 3 amount of auxiliary materials after granulation, mix well and then compress into tablets Get 2000 pine pollen sheet products (broken pine pollen content: 250 mg / sheet).
Embodiment 3
[0057] Example 3, 500 grams of broken pine pollen was soaked in 10 liters of 95% ethanol for 10 hours, percolated with 95% ethanol, and about 10 liters of 95% ethanol was added until the percolation liquid was almost colorless, and the percolation liquid was combined. Concentrate and recover ethanol below 40°C until there is no alcohol smell, and obtain about 102 grams of yellow syrupy extract. Mix the extract with 400 grams of cyclodextrin, add 400 milliliters of water, stir and grind for 1 hour. After the system becomes a viscous paste, dry it under reduced pressure at 50°C and pass through a 100-mesh sieve to obtain a light yellow solid package of pine pollen extract. Compound about 500 grams.
[0058] Add auxiliary materials to the obtained solid clathrate: 55 grams of microcrystalline cellulose, 40 grams of sodium starch glycolate, 2 grams of citric acid, 1 gram of fructose, and 2 grams of magnesium stearate; The mixture was fully mixed, dry granulated, and compressed in...
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