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Surgical prosthesis having biodegradable and nonbiodegradable regions

A technology of biodegradable and biodegradable materials, applied in the field of surgical prosthesis, can solve the problem of increased tissue strength

Active Publication Date: 2007-08-15
MAST BIOSURGERY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Have not had any specific exercise or any medications available to increase tissue strength

Method used

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  • Surgical prosthesis having biodegradable and nonbiodegradable regions

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Embodiment approach

[0056] According to another embodiment of the invention, the characteristic may comprise contributing to a significant fibroblastic response in the host tissue. The tissue ingrowth biodegradable region 12 can be configured to favor a fibrogenic response, while the anti-adhesion biodegradable region 14 preferably does not induce a fibrogenic response. The assisting effect of the tissue ingrowth biodegradable region 12 on the fibrogenesis response may be based on one or more of the above characteristics (e.g., biodegradation time or rate affected by additives, biodegradation time or rate affected by polymer structure / composition , and polymer compositions that affect strength or structural integrity), because the biodegradable surgical prosthesis 10 needs to maintain its structure long enough for the tissue to be firmly fixed.

[0057] In one embodiment, the tissue ingrowth biodegradable region 12 of the present invention may comprise or consist of at least one outer layer which...

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Abstract

A prosthesis for repairing a hernia includes an adhesion-resistant biodegradable region and an opposing tissue-ingrowth biodegradable region. When the prosthesis is implanted into the patient, the adhesion-resistant biodegradable region covers a fascial defect of the hernia, and the tissue-ingrowth biodegradable region is located above the adhesion-resistant biodegradable region while being exposed substantially only to the host's subcutaneous tissue layer. This orientation allows the tissue-ingrowth biodegradable region to become firmly incorporated with the host's body tissue. The adhesion-resistant biodegradable region faces the internal organs and decreases the incidence of adhesions and / or bowel obstruction.

Description

[0001] Cross References to Related Applications [0002] This application claims U.S. Provisional Application No. 60 / 601,414, filed August 13, 2004, entitled "SURGICAL PROSTHESIS HAVING BIODEGRADABLE AND NONBIODEGRADABLE REGIONS," (Attorney Docket: MB9800PR) and filed October 28, 2004, entitled " SURGICAL PROSTHESIS HAVING BIODEGRADABLE AND NONBIODEGRADABLE REGIONS," U.S. Provisional Application No. 60 / 623,524 (Attorney Docket: MB9828PR), the entire contents of which are incorporated herein by reference. This application is based on U.S. Application Nos. 10 / 631,980 (Attorney Docket: MA9604P), filed July 31, 2003, entitled "RESORBABLE THINMEMBRANES" and filed February 27, 2003, entitled "METHODS OF GOVERNING BONEGROWTH" US Application No. 10 / 375,451 (Attorney Docket: MA9608P), both of which are hereby incorporated by reference in their entirety. technical field [0003] This invention relates to surgical prostheses for repairing abdominal hernias. Background technique [0...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/02A61F2/04
CPCA61F2/0063A61F2250/0051A61F2/0077Y10T156/10A61F2210/0004A61F2/02A61F13/00
Inventor K·多伊施C·J·卡尔霍恩K·R·穆林斯
Owner MAST BIOSURGERY
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