Methods and materials for treating tumors

Abstract

This document provides methods and materials for treating a mammal (e.g., a human) having one or more tumors. For example, embolic agents including an amnion tissue preparation (e.g., amnion coated embolic agents) that can be used in arterial embolization to reduce or eliminate blood flow in a blood vessel that supplies a tumor are provided.

Description

BACKGROUND1. Technical Field[0001]This document relates to methods and materials for treating a mammal (e.g., a human) having one or more tumors. For example, embolic agents including an amnion tissue preparation (e.g., amnion coated embolic agents) provided herein can be used in arterial embolization to reduce and / or eliminate blood flow in a blood vessel that supplies a tumor.2. Background Information[0002]Cancer is among the leading causes of death in the United States and worldwide. In 2016, an estimated 1,685,210 new cases of cancer were diagnosed and 595,690 people died from the disease in the US alone (National Cancer Institute Cancer Statistics).SUMMARY[0003]This document provides methods and materials for treating a mammal (e.g., a human) having one or more tumors. For example, embolic agents including an amnion tissue preparation (e.g., embolic agents coated with an amnion tissue preparation, also referred to as “amnion coated embolic agents”) provided herein can be used i...

AI Technical Summary

Benefits of technology

The patent describes how to stop tumors from growing and surviving by cutting off the blood supply that brings them oxygen and nutrients. This method, known as vascular interruption, can remove the basis for tumor growth and lead to tumor cell death.

Problems solved by technology

Tumors cannot survive and grow without the oxygen and nutrients supplied by the vasculature.

As described herein, reducing and / or eliminating blood flow in a blood vessel that supplies a tumor can deprive the tumor of the oxygen-carrying blood and other substances it needs to grow, thereby starving the tumor cells.

The amnion tissue preparation can lack viable cells.